Teen suicide rate rises as prescribing of SSRIs falls, study finds

BMJ 2007; 335 doi: (Published 13 September 2007) Cite this as: BMJ 2007;335:531
  1. Owen Dyer
  1. London

    “Black box” labels ordered by the US Food and Drug Administration that warn of a greater risk of suicide from certain types of antidepressants may have had an effect opposite to that intended, says new research.

    Comparing numbers of prescriptions of selective serotonin reuptake inhibitors (SSRIs) and reported suicides in the United States and the Netherlands, the researchers found that the rate of suicides among children and adolescents rose as numbers of prescriptions of SSRIs fell in 2003-4 (American Journal of Psychiatry 2007;164:1356-63 doi: 10.1176/appi.ajp.2007.07030454).

    Numbers of suicides among Americans aged under 19 years rose by 14% from 2003 to 2004, the study says, the biggest annual …

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