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Rituximab works for severe pemphigus but there are serious side effects

BMJ 2007; 335 doi: (Published 16 August 2007) Cite this as: BMJ 2007;335:324

Twenty one patients with severe pemphigus who didn't respond to treatment with corticosteroids or in whom treatment with corticosteroids was contraindicated were given four weekly infusions of rituximab—a monoclonal antibody directed against the CD20 antigen of B lymphocytes. The drug …

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