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BMJ 2007; 335 doi: (Published 12 July 2007) Cite this as: BMJ 2007;335:104

Giving very sick patients nicotine replacement therapy may not be entirely safe, although it is sometimes given to smokers in the intensive care unit (ICU) to prevent withdrawal. A retrospective case-control analysis of this treatment in ICU patients found that it is associated with increased in-hospital mortality—20% in smokers who took the treatment versus 7% in those who did not. Treatment remained independently associated with increased mortality when severity of illness and invasive mechanical ventilation were adjusted for (Critical Care Medicine 2007;35:1517-21 doi: 10.1097/01.CCM.0000266537.86437.38).

What's happening to the price of eggs? A survey of ovum donor compensation rates in the US, set by members of the Society for Assisted Reproductive Technology, reports that the national average rate for standard donor compensation is $4217 (£2090; €3097) with a maximum reported price of $4576. Geographical variation is wide—the most expensive eggs are on the west and east coasts (Fertility and Sterility 2007;87:1001-4 doi: 10.1016/j.fertnstert.2006.12.037).

Delays in …

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