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Preoperative chemotherapy improves outcomes in non-small cell lung cancer

BMJ 2007; 334 doi: (Published 14 June 2007) Cite this as: BMJ 2007;334:1245

Surgery is the most effective treatment modality for resectable non-small cell lung carcinoma, but overall five year survival rates remain low. For decades trials failed to provide evidence that adjuvant chemotherapy has added value over surgery alone. In recent years, postoperative cisplatin and vinorelbine showed a sustained survival benefit of up to 15%, and some centres now use …

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