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Anakinra improves glycaemia in type 2 diabetes

BMJ 2007; 334 doi: (Published 19 April 2007) Cite this as: BMJ 2007;334:822

High blood glucose prompts pancreatic β cells to produce and release interleukin 1β, which inhibits the function of β cells and promotes their apoptosis. Its natural competitor for binding to the type I receptor, interleukin 1 receptor antagonist, protects β cells from …

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