When are randomised trials unnecessary? Picking signal from noise

BMJ 2007; 334 doi: (Published 22 March 2007) Cite this as: BMJ 2007;334:0-d

Paul Glasziou and colleagues used treatment for organophosphate poisoning as an example of a rapid effect that is easy to show (BMJ 2007;334:349-51, 17 Feb, doi: 10.1136/bmj.39070.527986.68). Success requires treatment with anticholinergic drugs, not with cholinesterase inhibitors as suggested.

View Abstract