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Aprotinin linked to excess deaths after coronary artery surgery

BMJ 2007; 334 doi: (Published 15 February 2007) Cite this as: BMJ 2007;334:336

Last year 246 000 Americans received aprotinin during coronary artery surgery. Aprotinin reduces bleeding and has been licensed for use during coronary artery surgery since 1993 in the United States. More recently, aprotinin has been linked to renal toxicity; cardiovascular, cerebrovascular, and pulmonary vascular …

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