Irish study shows women stop taking tamoxifen too early

BMJ 2007; 334 doi: (Published 08 February 2007) Cite this as: BMJ 2007;334:280
  1. Janice Hopkins Tanne
  1. 1New York

    A large Irish study of women who were prescribed tamoxifen showed that 22.1% had stopped taking the drug within a year (Cancer 2007 Jan 27, doi: 10.1002/cncr.22486). Within 3.5 years, the number who had stopped had risen to 35.2%.

    Thomas Barron and colleagues from Trinity College and St James's Hospital, Dublin, warn that the study raises concerns about patients failing to persist with oral hormonal treatments for breast cancer and oral antineoplastic agents in general.

    “Five years of adjuvant tamoxifen is the recommended treatment and results in a reduction in the relative breast cancer recurrence risk of 46% and the relative …

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