Intended for healthcare professionals


Prevention of diabetes: Lifestyle and metformin are the way forward

BMJ 2006; 333 doi: (Published 26 October 2006) Cite this as: BMJ 2006;333:918
  1. John S Ashcroft, general practitioner (
  1. Old Station Surgery, Ilkeston, Derbyshire DE7 8ES

    EDITOR—The concern expressed by Heneghan et al1 that drug treatment to prevent diabetes may not be as attractive as it first seems, may be justified for rosiglitazone but is not for metformin, which is effective, safe, and cheap.

    While the 31% reduction in new cases of diabetes with metformin in the Diabetes Prevention Program (DPP)2 seems unimpressive compared with the lifestyle groups' 58%, in …

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