Preoperative radiotherapy cuts recurrence of rectal cancerBMJ 2006; 333 doi: https://doi.org/10.1136/bmj.333.7572.773-b (Published 12 October 2006) Cite this as: BMJ 2006;333:773
- Toby Reynolds
Giving radiotherapy to patients with rectal cancer before surgery results in less risk of recurrence of local tumours than selective postoperative chemoradiotherapy. This is the finding of a new randomised trial, which also found that preoperative radiotherapy improves five year survival.
The CR07 trial, which was funded by the Medical Research Council, found that patients with resectable tumours benefited from preoperative radiotherapy whatever the size and position of the cancer or the quality of their excision surgery (Journal of Clinical Oncology 2006;24(18 suppl):S3511.
The study also found that the quality of surgical removal was directly related to the risk of recurrence. …