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Diethylstilbestrol increases risk of breast cancer death

BMJ 2006; 333 doi: (Published 06 July 2006) Cite this as: BMJ 2006;333:64
  1. Roger Dobson
  1. Abergavenny

    Women who took the drug diethylstilbestrol during pregnancy have an increased risk of death from breast cancer (British Journal of Cancer 2006;95:107-11).

    Results from the largest study to date of mortality outcomes in women who were exposed to the drug also show increased mortality from all causes. Diethylstilbestrol is a powerful non-steroidal oestrogen that was used to prevent pregnancy loss and complications for almost 30 years.

    The highest rates of breast cancer mortality were in women who had been in clinical trial with the drug and …

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