Intended for healthcare professionals


Care is needed before single test results are combined

BMJ 2006; 333 doi: (Published 29 June 2006) Cite this as: BMJ 2006;333:45
  1. G H Hall (, retired physician
  1. Exeter EX1 2HW

    EDITOR—Tonelli et al have provided valuable data for those interested in the interpretation of multiple test results. I differ, however, on the question of the evaluations of interaction and risk “additivity.”1

    It seems hard to believe that the interaction between the tests is of only “modest importance” when the odds of death are altered threefold for renal impairment and twofold for proteinuria (by the presence …

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