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At the time of our Mexico/Venezuela study on ITMs for dengue vector
control we had no information on comparative studies. The only similar one
was our CRT on sand flies in Venezuela.The sample size calculation was
done following the Hayes & Bennet paper quoted in the dengue
Nowadays, several years later, we are able to do sample size calculations
with much more precise assumptions based on this and other dengue vector
I am confused about the sample size calculation for this article. It
is explained that nine pairs of clusters were a conservative amount
because previously seven pairs had been calculated for a previous trial in
Trujillo. However, looking over that other trial in Trujillo, the study
was oriented to vector control for cutaneous leishmaniasis and does not
provide a lot of detail about sample size calculations. Could you please
clarify this issue?