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Trial of drug for trauma patients includes victims of Iraqi violence

BMJ 2006; 332 doi: (Published 25 May 2006) Cite this as: BMJ 2006;332:1234
  1. Owen Dyer
  1. London

    A major new trial will test a cheap, widely available drug that investigators hope could prevent tens of thousands of deaths from haemorrhage each year.

    The trial, the clinical randomisation of an antifibrinolytic in significant haemorrhage (CRASH-2) trial, will test the effects of tranexamic acid (TXA), an antifibrinolytic, on mortality and need for transfusion among adult trauma patients with ongoing major haemorrhage or who have a significant risk of haemorrhage.

    Among people aged between 5 years and 45 years worldwide trauma is second only to HIV and AIDS as a cause of death. Many of the three million patients …

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