Origin and funding of the most frequently cited papers in medicine: database analysis
BMJ 2006; 332 doi: https://doi.org/10.1136/bmj.38768.420139.80 (Published 04 May 2006) Cite this as: BMJ 2006;332:1061Data supplement
Appendix: Top cited papers in the domain of Clinical Medicine.
[Posted as supplied by the author]
Shown citation counts pertain directly to the main ISI record of each article and do not include citations under different records (e.g. those with different or mis-spelled names, volumes, or pages). Data are from Essential Science Indicators with corrections for some group authorship studies, as described in the Methods.
1994
Citations: 3,589
Title: A REVISED EUROPEAN-AMERICAN CLASSIFICATION OF LYMPHOID NEOPLASMS - A PROPOSAL FROM THE INTERNATIONAL LYMPHOMA STUDY-GROUP
Source: BLOOD 84: (5) 1361-1392 SEP 1 1994
Citations: 2,560
Title: SPECIFIC ASSOCIATION OF HUMAN TELOMERASE ACTIVITY WITH IMMORTAL CELLS AND CANCER
Source: SCIENCE 266: (5193) 2011-2015 DEC 23 1994
Citations: 2,322
Title: A COMPARISON OF BALLOON-EXPANDABLE-STENT IMPLANTATION WITH BALLOON ANGIOPLASTY IN PATIENTS WITH CORONARY-ARTERY DISEASE
Source: N ENGL J MED 331: (8) 489-495 AUG 25 1994
Citations: 2,213
Title: A STRONG CANDIDATE FOR THE BREAST AND OVARIAN-CANCER SUSCEPTIBILITY GENE BRCA1
Source: SCIENCE 266: (5182) 66-71 OCT 7 1994
Citations: 2,165
Title: MUTATION IN BLOOD-COAGULATION FACTOR-V ASSOCIATED WITH RESISTANCE TO ACTIVATED PROTEIN-C
Source: NATURE 369: (6475) 64-67 MAY 5 1994
Citations: 2,092
Title: IDENTIFICATION OF HERPESVIRUS-LIKE DNA-SEQUENCES IN AIDS-ASSOCIATED KAPOSIS-SARCOMA
Source: SCIENCE 266: (5192) 1865-1869 DEC 16 1994
Citations: 2,077
Title: A RANDOMIZED COMPARISON OF CORONARY-STENT PLACEMENT AND BALLOON ANGIOPLASTY IN THE TREATMENT OF CORONARY-ARTERY DISEASE
Source: N ENGL J MED 331: (8) 496-501 AUG 25 1994
Citations: 2,071
Title: A CELL-CYCLE REGULATOR POTENTIALLY INVOLVED IN GENESIS OF MANY TUMOR TYPES
Source: SCIENCE 264: (5157) 436-440 APR 15 1994
Citations: 1,972
Title: EFFICIENT PRESENTATION OF SOLUBLE-ANTIGEN BY CULTURED HUMAN DENDRITIC CELLS IS MAINTAINED BY GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR PLUS INTERLEUKIN-4 AND DOWN-REGULATED BY TUMOR-NECROSIS-FACTOR-ALPHA
Source: J EXP MED 179: (4) 1109-1118 APR 1 1994
Citations: 1,939
Title: MUTATIONS IN THE P53 TUMOR-SUPPRESSOR GENE - CLUES TO CANCER ETIOLOGY AND MOLECULAR PATHOGENESIS
Source: CANCER RES 54: (18) 4855-4878 SEP 15 1994
Citations: 1,663
Title: LEUKOCYTE-ENDOTHELIAL ADHESION MOLECULES
Source: BLOOD 84: (7) 2068-2101 OCT 1 1994
Citations: 1,563
Title: COLLABORATIVE OVERVIEW OF RANDOMIZED TRIALS OF ANTIPLATELET THERAPY .1. PREVENTION OF DEATH, MYOCARDIAL-INFARCTION, AND STROKE BY PROLONGED ANTIPLATELET THERAPY IN VARIOUS CATEGORIES OF PATIENTS
Source: BRITISH MEDICAL JOURNAL 308 (6921): 81-100 JAN 8 1994
Citations: 1,546
Title: GENETIC DISSECTION OF COMPLEX TRAITS
Source: SCIENCE 265: (5181) 2037-2048 SEP 30 1994
Citations: 1,514
Title: WAF1/CIP1 IS INDUCED IN P53-MEDIATED G(1) ARREST AND APOPTOSIS
Source: CANCER RES 54: (5) 1169-1174 MAR 1 1994
Citations: 1,450
Title: REDUCTION OF MATERNAL-INFANT TRANSMISSION OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 WITH ZIDOVUDINE TREATMENT
Source: N ENGL J MED 331: (18) 1173-1180 NOV 3 1994
Citations: 1,446
Title: A MATRIX METALLOPROTEINASE EXPRESSED ON THE SURFACE OF INVASIVE TUMOR-CELLS
Source: NATURE 370: (6484) 61-65 JUL 7 1994
Citations: 1,409
Title: INCREASING PREVALENCE OF OVERWEIGHT AMONG US ADULTS - THE NATIONAL-HEALTH AND NUTRITION EXAMINATION SURVEYS, 1960 TO 1991
Source: JAMA-J AM MED ASSN 272: (3) 205-211 JUL 20 1994
Citations: 1,393
Title: EFFECT OF VITAMIN-E AND BETA-CAROTENE ON THE INCIDENCE OF LUNG-CANCER AND OTHER CANCERS IN MALE SMOKERS
Source: N ENGL J MED 330 (15): 1029-1035 APR 14 1994
Citations: 1,360
Title: RANDOMIZED TRIAL OF CHOLESTEROL-LOWERING IN 4444 PATIENTS WITH CORONARY-HEART-DISEASE - THE SCANDINAVIAN SIMVASTATIN SURVIVAL STUDY (4S)
LANCET 344: (8934) 1383-1389 NOV 19 1994
Citations: 1,351
Title: CELL-CYCLE CONTROL AND CANCER
SCIENCE 266: (5192) 1821-1828 DEC 16 1994
Citations: 1,345
Title: TUMOR-SUPPRESSOR P53 IS A REGULATOR OF BCL-2 AND BAX GENE-EXPRESSION IN-VITRO AND IN-VIVO
Source: ONCOGENE 9: (6) 1799-1805 JUN 1994
Citations: 1,307
Title: P15(INK4B) IS A POTENTIAL EFFECTOR OF TGF-BETA-INDUCED CELL-CYCLE ARREST
Source: NATURE 371: (6494) 257-261 SEP 15 1994
Citations: 1,285
Title: DELETIONS OF THE CYCLIN-DEPENDENT KINASE-4 INHIBITOR GENE IN MULTIPLE HUMAN CANCERS
Source: NATURE 368: (6473) 753-756 APR 21 1994
Citations: 1,246
Title: MECHANISM OF ACTIVATION OF THE TGF-BETA RECEPTOR
Source: NATURE 370: (6488) 341-347 AUG 4 1994
Citations: 1,245
Title: EXCITATORY AMINO-ACIDS AS A FINAL COMMON PATHWAY FOR NEUROLOGIC DISORDERS
N ENGL J MED 330: (9) 613-622 MAR 3 1994
Citations: 1,240
Title: MUTATION IN THE DNA MISMATCH REPAIR GENE HOMOLOG HMLH1 IS ASSOCIATED WITH HEREDITARY NONPOLYPOSIS COLON-CANCER
Source: NATURE 368: (6468) 258-261 MAR 17 1994
Citations: 1,235
Title: MUTATION OF A MUTL HOMOLOG IN HEREDITARY COLON-CANCER
Source: SCIENCE 263: (5153) 1625-1629 MAR 18 1994
Citations: 1,211
Title: TRANSFORMING GROWTH-FACTOR-BETA IN TISSUE FIBROSIS
Source: N ENGL J MED 331: (19) 1286-1292 NOV 10 1994
Citations: 1197
Title: USE OF A MONOCLONAL-ANTIBODY DIRECTED AGAINST THE PLATELET GLYCOPROTEIN IIB/IIIA RECEPTOR IN HIGH-RISK CORONARY ANGIOPLASTY
Source: N ENGL J MED 330 (14): 956-961 APR 7 1994
Citations: 1,193
Title: CANCER STATISTICS, 1994
Source: CA-A CANCER J CLIN 44: (1) 7-26 JAN-FEB 1994
Citations: 1,142
Title: APOPTOSIS - ITS SIGNIFICANCE IN CANCER AND CANCER-THERAPY
Source: CANCER 73: (8) 2013-2026 APR 15 1994
Citations: 1,124
Title: THE P21 INHIBITOR OF CYCLIN-DEPENDENT KINASES CONTROLS DNA-REPLICATION BY INTERACTION WITH PCNA
Source: NATURE 369: (6481) 574-578 JUN 16 1994
Citations: 1,089
Title: REQUIREMENT OF VASCULAR INTEGRIN ALPHA(V)BETA(3) FOR ANGIOGENESIS
Source: SCIENCE 264: (5158) 569-571 APR 22 1994
1995
Citations: 3,427
Title: APOPTOSIS IN THE PATHOGENESIS AND TREATMENT OF DISEASE
Source: SCIENCE 267: (5203) 1456-1462 MAR 10 1995
Citations: 3,213
Title: PREVENTION OF CORONARY HEART-DISEASE WITH PRAVASTATIN IN MEN WITH HYPERCHOLESTEROLEMIA
Source: N ENGL J MED 333: (20) 1301-1307 NOV 16 1995
Citations: 2,669
Title: ANGIOGENESIS IN CANCER, VASCULAR, RHEUMATOID AND OTHER DISEASE
Source: NATURE MED 1: (1) 27-31 JAN 1995
Citations: 2,663
Title: OPPOSING EFFECTS OF ERK AND JNK-P38 MAP KINASES ON APOPTOSIS
Source: SCIENCE 270: (5240) 1326-1331 NOV 24 1995
Citations: 2,636
Title: THE FAS DEATH FACTOR
Source: SCIENCE 267: (5203) 1449-1456 MAR 10 1995
Citations: 2,337
Title: RAPID TURNOVER OF PLASMA VIRIONS AND CD4 LYMPHOCYTES IN HIV-1 INFECTION
Source: NATURE 373: (6510) 123-126 JAN 12 1995
Citations: 2,261
Title: IDENTIFICATION AND INHIBITION OF THE ICE/CED-3 PROTEASE NECESSARY FOR MAMMALIAN APOPTOSIS
Source: NATURE 376: (6535) 37-43 JUL 6 1995
Citations: 2,049
Title: INTEGRINS AND SIGNAL-TRANSDUCTION PATHWAYS - THE ROAD TAKEN
Source: SCIENCE 268: (5208) 233-239 APR 14 1995
Citations: 1,905
Title: INTERPRETING CHROMOSOMAL DNA RESTRICTION PATTERNS PRODUCED BY PULSED-FIELD GEL-ELECTROPHORESIS - CRITERIA FOR BACTERIAL STRAIN TYPING
Source: J CLIN MICROBIOL 33: (9) 2233-2239 SEP 1995
Citations: 1,759
Title: TISSUE-PLASMINOGEN ACTIVATOR FOR ACUTE ISCHEMIC STROKE
Source: N ENGL J MED 333 (24): 1581-1587 DEC 14 1995
Citations: 1,661
Title: A QUANTITATIVE ASSESSMENT OF PLASMA HOMOCYSTEINE AS A RISK FACTOR FOR VASCULAR-DISEASE - PROBABLE BENEFITS OF INCREASING FOLIC-ACID INTAKES
Source: JAMA-J AM MED ASSN 274: (13) 1049-1057 OCT 4 1995
Citations: 1,659
Title: MECHANISMS AND GENES OF CELLULAR SUICIDE
Source: SCIENCE 267: (5203) 1445-1449 MAR 10 1995
Citations: 1,476
Title: PHYSICAL-ACTIVITY AND PUBLIC-HEALTH - A RECOMMENDATION FROM THE CENTERS-FOR-DISEASE-CONTROL-AND-PREVENTION AND THE AMERICAN-COLLEGE-OF-SPORTS-MEDICINE
Source: JAMA-J AM MED ASSN 273: (5) 402-407 FEB 1 1995
Citations: 1,426
Title: SERIAL ANALYSIS OF GENE-EXPRESSION
Source: SCIENCE 270: (5235) 484-487 OCT 20 1995
Citations: 1,359
Title: FAILURE OF BLOOD-ISLAND FORMATION AND VASCULOGENESIS IN FLK-1-DEFICIENT MICE
Source: NATURE 376: (6535) 62-66 JUL 6 1995
Citations: 1,333
Title: LEPTIN LEVELS IN HUMAN AND RODENT - MEASUREMENT OF PLASMA LEPTIN AND OB RNA IN OBESE AND WEIGHT-REDUCED SUBJECTS
Source: NATURE MED 1: (11) 1155-1161 NOV 1995
Citations: 1,274
Title: INACTIVATION OF THE TYPE-II TGF-BETA RECEPTOR IN COLON-CANCER CELLS WITH MICROSATELLITE INSTABILITY
Source: SCIENCE 268: (5215) 1336-1338 JUN 2 1995
Citations: 1,273
Title: A SINGLE ATAXIA-TELANGIECTASIA GENE WITH A PRODUCT SIMILAR TO PI-3 KINASE
Source: SCIENCE 268: (5218) 1749-1753 JUN 23 1995
Citations: 1,266
Title: CANCER STATISTICS, 1995
Source: CA-A CANCER J CLIN 45: (1) 8-& JAN-FEB 1995
Citations: 1,251
Title: VASCULAR-PERMEABILITY FACTOR VASCULAR ENDOTHELIAL GROWTH-FACTOR, MICROVASCULAR HYPERPERMEABILITY, AND ANGIOGENESIS
Source: AMER J PATHOL 146: (5) 1029-1039 MAY 1995
Citations: 1,225
Title: APOPTOSIS, ONCOSIS, AND NECROSIS - AN OVERVIEW OF CELL-DEATH
Source: AMER J PATHOL 146: (1) 3-15 JAN 1995
Citations: 1,221
Title: ENDARTERECTOMY FOR ASYMPTOMATIC CAROTID-ARTERY STENOSIS
Source: JAMA 273 (18): 1421-1428 MAY 10 1995
Citations: 1,156
Title: EFFECTS OF ESTROGEN OR ESTROGEN/PROGESTIN REGIMENS ON HEART-DISEASE RISK-FACTORS IN POSTMENOPAUSAL WOMEN - THE POSTMENOPAUSAL ESTROGEN/PROGESTIN INTERVENTIONS (PEPI) TRIAL
Source: JAMA 273 (3): 199-208 JAN 18 1995
Citations: 1,154
Title: EARLY REDISTRIBUTION OF PLASMA-MEMBRANE PHOSPHATIDYLSERINE IS A GENERAL FEATURE OF APOPTOSIS REGARDLESS OF THE INITIATING STIMULUS - INHIBITION BY OVEREXPRESSION OF BCL-2 AND ABL
Source: J EXP MED 182: (5) 1545-1556 NOV 1 1995
Citations: 1,106
Title: FAS LIGAND-INDUCED APOPTOSIS AS A MECHANISM OF IMMUNE PRIVILEGE
Source: SCIENCE 270: (5239) 1189-1192 NOV 17 1995
Citations: 1,099
Title: IMMUNOSUPPRESSION BY GLUCOCORTICOIDS - INHIBITION OF NF-KAPPA-B ACTIVITY THROUGH INDUCTION OF I-KAPPA-B SYNTHESIS
Source: SCIENCE 270: (5234) 286-290 OCT 13 1995
Citations: 1,097
Title: PREVALENCE OF HUMAN PAPILLOMAVIRUS IN CERVICAL-CANCER - A WORLDWIDE PERSPECTIVE
Source: J NAT CANCER INST 87: (11) 796-802 JUN 7 1995
Citations: 1,082
Title: SEMINARS IN MEDICINE OF THE BETH ISRAEL HOSPITAL, BOSTON - CLINICAL APPLICATIONS OF RESEARCH ON ANGIOGENESIS
Source: N ENGL J MED 333: (26) 1757-1763 DEC 28 1995
Citations: 1,070
Title: IDENTIFICATION OF THE BREAST-CANCER SUSCEPTIBILITY GENE BRCA2
Source: NATURE 378: (6559) 789-792 DEC 21 1995
Citations: 1,067
Title: 5' CPG ISLAND METHYLATION IS ASSOCIATED WITH TRANSCRIPTIONAL SILENCING OF THE TUMOR-SUPPRESSOR P16/CDKN2/MTS1 IN HUMAN CANCERS
Source: NATURE MED 1: (7) 686-692 JUL 1995
Citations: 1,065
Title: DENDRITIC CELLS USE MACROPINOCYTOSIS AND THE MANNOSE RECEPTOR TO CONCENTRATE MACROMOLECULES IN THE MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II COMPARTMENT - DOWN-REGULATION BY CYTOKINES AND BACTERIAL PRODUCTS
Source: J EXP MED 182: (2) 389-400 AUG 1 1995
Citations: 1,056
Title: THE RNA COMPONENT OF HUMAN TELOMERASE
Source: SCIENCE 269: (5228) 1236-1241 SEP 1 1995
Citations: 1,049
Title: KAPOSIS SARCOMA-ASSOCIATED HERPESVIRUS-LIKE DNA-SEQUENCES IN AIDS-RELATED BODY-CAVITY-BASED LYMPHOMAS
Source: N ENGL J MED 332: (18) 1186-1191 MAY 4 1995
1996
Citations: 2,840
Title: THE EFFECT OF PRAVASTATIN ON CORONARY EVENTS AFTER MYOCARDIAL INFARCTION IN PATIENTS WITH AVERAGE CHOLESTEROL LEVELS
Source: N ENGL J MED 335: (14) 1001-1009 OCT 3 1996
Citations: 2,333
Title: CANCER CELL CYCLES
Source: SCIENCE 274: (5293) 1672-1677 DEC 6 1996
Citations: 2,000
Title: SERUM IMMUNOREACTIVE LEPTIN CONCENTRATIONS IN NORMAL-WEIGHT AND OBESE HUMANS
Source: N ENGL J MED 334: (5) 292-295 FEB 1 1996
Citations: 1,681
Title: AN ESSENTIAL ROLE FOR NF-KAPPA B IN PREVENTING TNF-ALPHA-INDUCED CELL DEATH
Source: SCIENCE 274: (5288) 782-784 NOV 1 1996
Citations: 1,581
Title: THE EFFECT OF CARVEDILOL ON MORBIDITY AND MORTALITY IN PATIENTS WITH CHRONIC HEART FAILURE
Source: N ENGL J MED 334: (21) 1349-1355 MAY 23 1996
Citations: 1,526
Title: TNF- AND CANCER THERAPY-INDUCED APOPTOSIS: POTENTIATION BY INHIBITION OF NF-KAPPA B
Source: SCIENCE 274: (5288) 784-787 NOV 1 1996
Citations: 1,360
Title: BIOLOGIC BASIS FOR INTERLEUKIN-1 IN DISEASE
Source: BLOOD 87: (6) 2095-2147 MAR 15 1996
Citations: 1,299
Title: METHYLATION-SPECIFIC PCR: A NOVEL PCR ASSAY FOR METHYLATION STATUS OF CPG ISLANDS
Source: PROC NAT ACAD SCI USA 93: (18) 9821-9826 SEP 3 1996
Citations: 1,288
Title: PROGNOSIS IN HIV-1 INFECTION PREDICTED BY THE QUANTITY OF VIRUS IN PLASMA
Source: SCIENCE 272: (5265) 1167-1170 MAY 24 1996
Citations: 1,280
Title: A RANDOMISED, BLINDED, TRIAL OF CLOPIDOGREL VERSUS ASPIRIN IN PATIENTS AT RISK OF ISCHAEMIC EVENTS (CAPRIE)
Source: LANCET 348 (9038): 1329-1339 NOV 16 1996
Citations: 1,248
Title: IN VIVO GENE DELIVERY AND STABLE TRANSDUCTION OF NONDIVIDING CELLS BY A LENTIVIRAL VECTOR
Source: SCIENCE 272: (5259) 263-267 APR 12 1996
Citations: 1,199
Title: A COMMON GENETIC VARIATION IN THE 3'-UNTRANSLATED REGION OF THE PROTHROMBIN GENE IS ASSOCIATED WITH ELEVATED PLASMA PROTHROMBIN LEVELS AND AN INCREASE IN VENOUS THROMBOSIS
Source: BLOOD 88: (10) 3698-3703 NOV 15 1996
Citations: 1,153
Title: ABNORMAL BLOOD VESSEL DEVELOPMENT AND LETHALITY IN EMBRYOS LACKING A SINGLE VEGF ALLELE
Source: NATURE 380: (6573) 435-439 APR 4 1996
Citations: 1,134
Title: DPC4, A CANDIDATE TUMOR SUPPRESSOR GENE AT HUMAN CHROMOSOME 18Q21.1
Source: SCIENCE 271: (5247) 350-353 JAN 19 1996
Citations: 1,097
Title: HETEROZYGOUS EMBRYONIC LETHALITY INDUCED BY TARGETED INACTIVATION OF THE VEGF GENE
Source: NATURE 380: (6573) 439-442 APR 4 1996
Citations: 1,083
Title: EFFECTS OF A COMBINATION OF BETA CAROTENE AND VITAMIN A ON LUNG CANCER AND CARDIOVASCULAR DISEASE
Source: N ENGL J MED 334: (18) 1150-1155 MAY 2 1996
Citations: 1,079
Title: EVIDENCE BASED MEDICINE: WHAT IT IS AND WHAT IT ISN’T
Source: BRITISH MEDICAL JOURNAL 312 (7023): 71-72 JAN 13 1996
Citations: 1,053
Title: A NEW VARIANT OF CREUTZFELDT-JAKOB DISEASE IN THE UK
Source: LANCET 347: (9006) 921-925 APR 6 1996
Citations: 1,052
Title: CANCER STATISTICS, 1996
Source: CA-A CANCER J CLIN 46: (1) 5-27 JAN-FEB 1996
Citations: 1,050
Title: MOLECULAR CLONING AND DISEASE ASSOCIATION OF HEPATITIS G VIRUS: A TRANSFUSION-TRANSMISSIBLE AGENT
Source: SCIENCE 271: (5248) 505-508 JAN 26 1996
Citations: 1,018
Title: CLASSIFICATION AND GRADING OF GASTRITIS - THE UPDATED SYDNEY SYSTEM
Source: AMER J SURG PATHOL 20: (10) 1161-1181 OCT 1996
Citations: 1,017
Title: HIV-1 DYNAMICS IN VIVO: VIRION CLEARANCE RATE, INFECTED CELL LIFE-SPAN, AND VIRAL GENERATION TIME
Source: SCIENCE 271: (5255) 1582-1586 MAR 15 1996
Citations: 1,012
Title: RANDOMISED CONTROLLED TRIAL OF VITAMIN E IN PATIENTS WITH CORONARY DISEASE: CAMBRIDGE HEART ANTIOXIDANT STUDY (CHAOS)
Source: LANCET 347: (9004) 781-786 MAR 23 1996
Citations: 1,007
Title: CYCLOPHOSPHAMIDE AND CISPLATIN COMPARED WITH PACLITAXEL AND CISPLATIN IN PATIENTS WITH STAGE III AND STAGE IV OVARIAN CANCER
Source: N ENGL J MED 334: (1) 1-6 JAN 4 1996
Citations: 1,001
Title: LIGATION OF CD40 ON DENDRITIC CELLS TRIGGERS PRODUCTION OF HIGH LEVELS OF INTERLEUKIN-12 AND ENHANCES T CELL STIMULATORY CAPACITY: T-T HELP VIA APC ACTIVATION
Source: J EXP MED 184: (2) 747-752 AUG 1 1996
Citations: 984
Title: SECRETED AMYLOID BETA-PROTEIN SIMILAR TO THAT IN THE SENILE PLAQUES OF ALZHEIMER'S DISEASE IS INCREASED IN VIVO BY THE PRESENILIN 1 AND 2 AND APP MUTATIONS LINKED TO FAMILIAL ALZHEIMER'S DISEASE
Source: NATURE MED 2: (8) 864-870 AUG 1996
Citations: 980
Title: SUPPRESSION SUBTRACTIVE HYBRIDIZATION: A METHOD FOR GENERATING DIFFERENTIALLY REGULATED OR TISSUE-SPECIFIC CDNA PROBES AND LIBRARIES
Source: PROC NAT ACAD SCI USA 93: (12) 6025-6030 JUN 11 1996
Citations: 974
Title: HYPOXIA-MEDIATED SELECTION OF CELLS WITH DIMINISHED APOPTOTIC POTENTIAL IN SOLID TUMOURS
Source: NATURE 379: (6560) 88-91 JAN 4 1996
Citations: 949
Title: RANDOMISED TRIAL OF EFFECT OF ALENDRONATE ON RISK OF FRACTURE IN WOMEN WITH EXISTING VERTEBRAL FRACTURES
Source: LANCET 348 (9041): 1535-1541 DEC 7 1996
Citations: 946
Title: VACCINATION OF PATIENTS WITH B-CELL LYMPHOMA USING AUTOLOGOUS ANTIGEN-PULSED DENDRITIC CELLS
Source: NATURE MED 2: (1) 52-58 JAN 1996
Citations: 940
Title: LACK OF EFFECT OF LONG-TERM SUPPLEMENTATION WITH BETA CAROTENE ON THE INCIDENCE OF MALIGNANT NEOPLASMS AND CARDIOVASCULAR DISEASE
Source: N ENGL J MED 334: (18) 1145-1149 MAY 2 1996
Citations: 917
Title: RANDOMISED TRIAL OF EFFECT OF ALENDRONATE ON RISK OF FRACTURE IN WOMEN WITH EXISTING VERTEBRAL FRACTURES
Source: LANCET 348: (9041) 1535-1541 DEC 7 1996
Citations: 859
Title: A RANDOMIZED COMPARISON OF ANTIPLATELET AND ANTICOAGULANT THERAPY AFTER THE PLACEMENT OF CORONARY-ARTERY STENTS
Source: N ENGL J MED 334: (17) 1084-1089 APR 25 1996
1997
Citations: 2,272
Title: PREVENTION OF APOPTOSIS BY BCL-2: RELEASE OF CYTOCHROME C FROM MITOCHONDRIA BLOCKED
Source: SCIENCE 275: (5303) 1129-1132 FEB 21 1997
Citations: 2,221
Title: THE RELEASE OF CYTOCHROME C FROM MITOCHONDRIA: A PRIMARY SITE FOR BCL-2 REGULATION OF APOPTOSIS
Source: SCIENCE 275: (5303) 1132-1136 FEB 21 1997
Citations: 1,675
Title: INFLAMMATION, ASPIRIN, AND THE RISK OF CARDIOVASCULAR DISEASE IN APPARENTLY HEALTHY MEN
Source: N ENGL J MED 336: (14) 973-979 APR 3 1997
Citations: 1,434
Title: CANCER STATISTICS, 1997
Source: CA-A CANCER J CLIN 47: (1) 5-27 JAN-FEB 1997
Citations: 1,407
Title: MECHANISMS OF ANGIOGENESIS
Source: NATURE 386: (6626) 671-674 APR 17 1997
Citations: 1,299
Title: A CONTROLLED TRIAL OF TWO NUCLEOSIDE ANALOGUES PLUS INDINAVIR IN PERSONS WITH HUMAN IMMUNODEFICIENCY VIRUS INFECTION AND CD4 CELL COUNTS OF 200 PER CUBIC MILLIMETER OR LESS
Source: N ENGL J MED 337: (11) 725-733 SEP 11 1997
Citations: 1,298
Title: PTEN, A PUTATIVE PROTEIN TYROSINE PHOSPHATASE GENE MUTATED IN HUMAN BRAIN, BREAST, AND PROSTATE CANCER
Source: SCIENCE 275: (5308) 1943-1947 MAR 28 1997
Citations: 1,290
Title: ACTIVATION OF BETA-CATENIN-TCF SIGNALING IN COLON CANCER BY MUTATIONS IN BETA-CATENIN OR APC
Source: SCIENCE 275: (5307) 1787-1790 MAR 21 1997
Citations: 1,275
Title: MECHANISMS OF DISEASE - NUCLEAR FACTOR-KAPPA B - A PIVOTAL TRANSCRIPTION FACTOR IN CHRONIC INFLAMMATORY DISEASES
Source: N ENGL J MED 336: (15) 1066-1071 APR 10 1997
Citations: 1,196
Title: CHEMOKINES
Source: BLOOD 90: (3) 909-928 AUG 1 1997
Citations: 1,180
Title: MDM2 PROMOTES THE RAPID DEGRADATION OF P53
Source: BLOOD 90: (3) 909-928 AUG 1 1997
Citations: 1,169
Title: THE SIXTH REPORT OF THE JOINT NATIONAL COMMITTEE ON PREVENTION, DETECTION, EVALUATION, AND TREATMENT OF HIGH BLOOD PRESSURE
Source: ARCH INTERN MED 157: (21) 2413-2446 NOV 24 1997
Citations: 1,120
Title: REVISIONS IN THE INTERNATIONAL SYSTEM FOR STAGING LUNG CANCER
Source: CHEST 111: (6) 1710-1717 JUN 1997
Citations: 1,114
Title: PLATELET GLYCOPROTEIN IIb/IIIa RECEPTOR BLOCKADE AND LOW-DOSE HEPARIN DURING PERCUTANEOUS CORONARY REVASCULARIZATION
Source: N ENGL J MED 336 (24): 1689-1696 JUN 12 1997
Citations: 1,077
Title: A MODEL FOR P53-INDUCED APOPTOSIS
Source: NATURE 389: (6648) 300-305 SEP 18 1997
Citations: 1,066
Title: VIABLE OFFSPRING DERIVED FROM FETAL AND ADULT MAMMALIAN CELLS
Source: NATURE 385: (6619) 810-813 FEB 27 1997
Citations: 1,062
Title: CONSTITUTIVE TRANSCRIPTIONAL ACTIVATION BY A BETA-CATENIN-TCF COMPLEX IN APC(-/-) COLON CARCINOMA
Source: SCIENCE 275: (5307) 1784-1787 MAR 21 1997
Citations: 1,049
Title: THE PROTO-ONCOGENE BCL-2 AND ITS ROLE IN REGULATING APOPTOSIS
Source: NATURE MED 3: (6) 614-620 JUN 1997
Citations: 1,015
Title: REGULATION OF P53 STABILITY BY MDM2
Source: NATURE 387: (6630) 299-303 MAY 15 1997
Citations: 997
Title: RANDOMISED DOUBLE-BLIND COMPARISON OF PLACEBO AND ACTIVE TREATMENT FOR OLDER PATIENTS WITH ISOLATED SYSTOLIC HYPERTENSION
Source: LANCET 350: (9080) 757-764 SEP 13 1997
Citations: 979
Title: DIFFERENTIAL LIGAND ACTIVATION OF ESTROGEN RECEPTORS ER ALPHA AND ER BETA AT AP1 SITES
Source: SCIENCE 277: (5331) 1508-1510 SEP 5 1997
Citations: 946
Title: INHIBITION OF DEATH RECEPTOR SIGNALS BY CELLULAR FLIP
Source: NATURE 388: (6638) 190-195 JUL 10 1997
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Title: A SHORT-TERM STUDY OF CHIMERIC MONOCLONAL ANTIBODY CA2 TO TUMOR NECROSIS FACTOR ALPHA FOR CROHN'S DISEASE
Source: N ENGL J MED 337: (15) 1029-1035 OCT 9 1997
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Title: TELOMERASE CATALYTIC SUBUNIT HOMOLOGS FROM FISSION YEAST AND HUMAN
Source: SCIENCE 277: (5328) 955-959 AUG 15 1997
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Title: TREATMENT WITH INDINAVIR, ZIDOVUDINE, AND LAMIVUDINE IN ADULTS WITH HUMAN IMMUNODEFICIENCY VIRUS INFECTION AND PRIOR ANTIRETROVIRAL THERAPY
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Title: BREAST CANCER AND HORMONE REPLACEMENT THERAPY: COLLABORATIVE REANALYSIS OF DATA FROM 51 EPIDEMIOLOGICAL STUDIES OF 52,705 WOMEN WITH BREAST CANCER AND 108,411 WOMEN WITHOUT BREAST CANCER
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Title: REPORT OF THE EXPERT COMMITTEE ON THE DIAGNOSIS AND CLASSIFICATION OF DIABETES MELLITUS
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Title: DOUBLE IDENTITY FOR PROTEINS OF THE BCL-2 FAMILY
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Title: LIVER REGENERATION
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1998
Citations: 3,572
Title: DENDRITIC CELLS AND THE CONTROL OF IMMUNITY
Source: NATURE 392: (6673) 245-252 MAR 19 1998
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Title: MITOCHONDRIA AND APOPTOSIS
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Title: CLUSTER ANALYSIS AND DISPLAY OF GENOME-WIDE EXPRESSION PATTERNS
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Source: N ENGL J MED 338: (13) 853-860 MAR 26 1998
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Title: CASPASES: ENEMIES WITHIN
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Title: RANDOMIZED TRIAL OF ESTROGEN PLUS PROGESTIN FOR SECONDARY PREVENTION OF CORONARY HEART DISEASE IN POSTMENOPAUSAL WOMEN
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Title: DEATH RECEPTORS: SIGNALING AND MODULATION
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Title: THE BCL-2 PROTEIN FAMILY: ARBITERS OF CELL SURVIVAL
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Title: PREVENTION OF CARDIOVASCULAR EVENTS AND DEATH WITH PRAVASTATIN IN PATIENTS WITH CORONARY HEART DISEASE AND A BROAD RANGE OF INITIAL CHOLESTEROL LEVELS
Source: N ENGL J MED 339 (19): 1349-1357 NOV 5 1998
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Title: PRIMARY PREVENTION OF ACUTE CORONARY EVENTS WITH LOVASTATIN IN MEN AND WOMEN WITH AVERAGE CHOLESTEROL LEVELS - RESULTS OF AFCAPS/TEXCAPS
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Title: EFFECTS OF INTENSIVE BLOOD-PRESSURE LOWERING AND LOW-DOSE ASPIRIN IN PATIENTS WITH HYPERTENSION: PRINCIPAL RESULTS OF THE HYPERTENSION OPTIMAL TREATMENT (HOT) RANDOMISED TRIAL
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Citations: 1,478
Title: CANCER STATISTICS, 1998
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Title: A CASPASE-ACTIVATED DNASE THAT DEGRADES DNA DURING APOPTOSIS, AND ITS INHIBITOR ICAD
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Citations: 1,421
Title: EXTENSION OF LIFE-SPAN BY INTRODUCTION OF TELOMERASE INTO NORMAL HUMAN CELLS
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Title: VACCINATION OF MELANOMA PATIENTS WITH PEPTIDE- OR TUMOR LYSATE-PULSED DENDRITIC CELLS
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Title: INTENSIVE BLOOD-GLUCOSE CONTROL WITH SULPHONYLUREAS OR INSULIN COMPARED WITH CONVENTIONAL TREATMENT AND RISK OF COMPLICATIONS IN PATIENTS WITH TYPE 2 DIABETES (UKPDS 33
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Title: TRENDS IN ALTERNATIVE MEDICINE USE IN THE UNITED STATES, 1990-1997 - RESULTS OF A FOLLOW-UP NATIONAL SURVEY
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Title: INTERFERON ALFA-2B ALONE OR IN COMBINATION WITH RIBAVIRIN AS INITIAL TREATMENT FOR CHRONIC HEPATITIS C
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Title: TAMOXIFEN FOR EARLY BREAST CANCER: AN OVERVIEW OF THE RANDOMISED TRIALS
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Title: CHEMOKINES - CHEMOTACTIC CYTOKINES THAT MEDIATE INFLAMMATION
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Title: IDENTIFICATION OF C-MYC AS A TARGET OF THE APC PATHWAY
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Title: NF-KAPPA B ANTIAPOPTOSIS: INDUCTION OF TRAF1 AND TRAF2 AND C-IAP1 AND C-IAP2 TO SUPPRESS CASPASE-8 ACTIVATION
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Title: CHEMOKINES AND LEUKOCYTE TRAFFIC
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Title: GENETIC INSTABILITIES IN HUMAN CANCERS
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1999
Citations: 3,813
Title: MECHANISMS OF DISEASE - ATHEROSCLEROSIS - AN INFLAMMATORY DISEASE
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Title: CANCER STATISTICS, 1999
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Title: THE EFFECT OF SPIRONOLACTONE ON MORBIDITY AND MORTALITY IN PATIENTS WITH SEVERE HEART FAILURE
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Citations: 1,149
Title: THE CARDIAC INSUFFICIENCY BISOPROLOL STUDY II (CIBIS-II): A RANDOMISED TRIAL
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Citations: 1,142
Title: MULTILINEAGE POTENTIAL OF ADULT HUMAN MESENCHYMAL STEM CELLS
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Title: EFFECT OF METOPROLOL CR XL IN CHRONIC HEART FAILURE: MERIT-HF
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Title: MOLECULAR CHARACTERIZATION OF MITOCHONDRIAL APOPTOSIS-INDUCING FACTOR
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Title: BETA-CATENIN REGULATES EXPRESSION OF CYCLIN D1 IN COLON CARCINOMA CELLS
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Title: FOOD-RELATED ILLNESS AND DEATH IN THE UNITED STATES
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Title: GEMFIBROZIL FOR THE SECONDARY PREVENTION OF CORONARY HEART DISEASE IN MEN WITH LOW LEVELS OF HIGH-DENSITY LIPOPROTEIN CHOLESTEROL
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Citations: 800
Title: DIETARY SUPPLEMENTATION WITH N-3 POLYUNSATURATED FATTY ACIDS AND VITAMIN E AFTER MYOCARDIAL INFARCTION: RESULTS OF THE GISSI-PREVENZIONE TRIAL
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Title: 1999 WORLD HEALTH ORGANIZATION INTERNATIONAL SOCIETY OF HYPERTENSION GUIDELINES FOR THE MANAGEMENT OF HYPERTENSION
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Title: INTERPRETING PATTERNS OF GENE EXPRESSION WITH SELF-ORGANIZING MAPS: METHODS AND APPLICATION TO HEMATOPOIETIC DIFFERENTIATION
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Citations: 749
Title: THE TUMOUR SUPPRESSOR PROTEIN VHL TARGETS HYPOXIA-INDUCIBLE FACTORS FOR OXYGEN-DEPENDENT PROTEOLYSIS
Source: NATURE 399: (6733) 271-275 MAY 20 1999
Citations: 705
Title: WORLD HEALTH ORGANIZATION CLASSIFICATION OF NEOPLASTIC DISEASES OF THE HEMATOPOIETIC AND LYMPHOID TISSUES: REPORT OF THE CLINICAL ADVISORY COMMITTEE MEETING - AIRLIE HOUSE, VIRGINIA, NOVEMBER 1997
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Title: REDUCTION OF VERTEBRAL FRACTURE RISK IN POSTMENOPAUSAL WOMEN WITH OSTEOPOROSIS TREATED WITH RALOXIFENE - RESULTS FROM A 3-YEAR RANDOMIZED CLINICAL TRIAL
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Title: HUMAN PAPILLOMAVIRUS IS A NECESSARY CAUSE OF INVASIVE CERVICAL CANCER WORLDWIDE
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Title: THE PROTECTIVE EFFECTS OF ESTROGEN ON THE CARDIOVASCULAR SYSTEM
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Title: THE PREVALENCE OF HEPATITIS C VIRUS INFECTION IN THE UNITED STATES, 1988 THROUGH 1994
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Title: ACTIVATION OF NITRIC OXIDE SYNTHASE IN ENDOTHELIAL CELLS BY AKT-DEPENDENT PHOSPHORYLATION
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Title: CAROTID-ARTERY INTIMA AND MEDIA THICKNESS AS A RISK FACTOR FOR MYOCARDIAL INFARCTION AND STROKE IN OLDER ADULTS
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Citations: 649
Title: BONE MARROW AS A POTENTIAL SOURCE OF HEPATIC OVAL CELLS
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Title: TURNING BRAIN INTO BLOOD: A HEMATOPOIETIC FATE ADOPTED BY ADULT NEURAL STEM CELLS IN VIVO
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Title: CREATION OF HUMAN TUMOUR CELLS WITH DEFINED GENETIC ELEMENTS
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Citations: 632
Title: EFFECT OF ANGIOTENSIN-CONVERTING ENZYME INHIBITION COMPARED WITH CONVENTIONAL THERAPY ON CARDIOVASCULAR MORBIDITY AND MORTALITY IN HYPERTENSION: THE CAPTOPRIL PREVENTION PROJECT (CAPPP) RANDOMISED TRIAL
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Title: GLOBAL BURDEN OF TUBERCULOSIS - ESTIMATED INCIDENCE, PREVALENCE, AND MORTALITY BY COUNTRY
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Citations: 629
Title: NF-KAPPA B IS A TARGET OF AKT IN ANTI-APOPTOTIC PDGF SIGNALLING
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Citations: 626
Title: MECHANISMS OF DISEASE: ACUTE-PHASE PROTEINS AND OTHER SYSTEMIC RESPONSES TO INFLAMMATION
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Citations: 620
Title: OPGL IS A KEY REGULATOR OF OSTEOCLASTOGENESIS, LYMPHOCYTE DEVELOPMENT AND LYMPH-NODE ORGANOGENESIS
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Title: NF-KAPPA B ACTIVATION BY TUMOUR NECROSIS FACTOR REQUIRES THE AKT SERINE-THREONINE KINASE
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Title: TUMORICIDAL ACTIVITY OF TUMOR NECROSIS FACTOR RELATED APOPTOSIS-INDUCING LIGAND IN VIVO
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Title: THE EFFECT OF RALOXIFENE ON RISK OF BREAST CANCER IN POSTMENOPAUSAL WOMEN - RESULTS FROM THE MORE RANDOMIZED TRIAL
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Title: INFLIXIMAB FOR THE TREATMENT OF FISTULAS IN PATIENTS WITH CROHN'S DISEASE
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2000
Citations: 1,637
Title: CANCER STATISTICS, 2000
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Title: DISTINCT TYPES OF DIFFUSE LARGE B-CELL LYMPHOMA IDENTIFIED BY GENE EXPRESSION PROFILING
Source: NATURE 403: (6769) 503-511 FEB 3 2000
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Title: EFFECTS OF AN ANGIOTENSIN-CONVERTING-ENZYME INHIBITOR, RAMIPRIL, ON CARDIOVASCULAR EVENTS IN HIGH-RISK PATIENTS
Source: N ENGL J MED 342: (3) 145-153 JAN 20 2000
Citations: 1,133
Title: THE BIOCHEMISTRY OF APOPTOSIS
Source: NATURE 407: (6805) 770-776 OCT 12 2000
Citations: 951
Title: ANGIOGENESIS IN CANCER AND OTHER DISEASES
Source: NATURE 407: (6801) 249-257 SEP 14 2000
Citations: 876
Title: MITOCHONDRIAL CONTROL OF CELL DEATH
Source: NATURE MED 6: (5) 513-519 MAY 2000
Citations: 876
Title: MOLECULAR PORTRAITS OF HUMAN BREAST TUMOURS
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Title: COMPARISON OF UPPER GASTROINTESTINAL TOXICITY OF ROFECOXIB AND NAPROXEN IN PATIENTS WITH RHEUMATOID ARTHRITIS
Source: N ENGL J MED 343: (21) 1520-1528 NOV 23 2000
Citations: 829
Title: C-REACTIVE PROTEIN AND OTHER MARKERS OF INFLAMMATION IN THE PREDICTION OF CARDIOVASCULAR DISEASE IN WOMEN
Source: N ENGL J MED 342: (12) 836-843 MAR 23 2000
Citations: 786
Title: GASTROINTESTINAL TOXICITY WITH CELECOXIB VS NONSTEROIDAL ANTI-INFLAMMATORY DRUGS FOR OSTEOARTHRITIS AND RHEUMATOID ARTHRITIS - THE CLASS STUDY: A RANDOMIZED CONTROLLED TRIAL
Source: JAMA-J AM MED ASSN 284: (10) 1247-1255 SEP 13 2000
Citations: 751
Title: SURFING THE P53 NETWORK
Source: NATURE 408: (6810) 307-310 NOV 16 2000
Citations: 696
Title: ISLET TRANSPLANTATION IN SEVEN PATIENTS WITH TYPE 1 DIABETES MELLITUS USING A GLUCOCORTICOID-FREE IMMUNOSUPPRESSIVE REGIMEN
Source: N ENGL J MED 343: (4) 230-238 JUL 27 2000
Citations: 644
Title: PURIFIED HEMATOPOIETIC STEM CELLS CAN DIFFERENTIATE INTO HEPATOCYTES IN VIVO
Source: NATURE MED 6: (11) 1229-1234 NOV 2000
Citations: 643
Title: VASCULAR-SPECIFIC GROWTH FACTORS AND BLOOD VESSEL FORMATION
Source: NATURE 407: (6801) 242-248 SEP 14 2000
Citations: 618
Title: INFLIXIMAB AND METHOTREXATE IN THE TREATMENT OF RHEUMATOID ARTHRITIS
Source: N ENGL J MED 343: (22) 1594-1602 NOV 30 2000
Citations: 616
Title: THE EFFECT OF CELECOXIB, A CYCLOOXYGENASE-2 INHIBITOR, IN FAMILIAL ADENOMATOUS POLYPOSIS
Source: N ENGL J MED 342: (26) 1946-1952 JUN 29 2000
Citations: 591
Title: GENE THERAPY OF HUMAN SEVERE COMBINED IMMUNODEFICIENCY (SCID)-X1 DISEASE
Source: SCIENCE 288: (5466) 669-672 APR 28 2000
Citations: 587
Title: VENTILATION WITH LOWER TIDAL VOLUMES AS COMPARED WITH TRADITIONAL TIDAL VOLUMES FOR ACUTE LUNG INJURY AND THE ACUTE RESPIRATORY DISTRESS SYNDROME
Source: N ENGL J MED 342: (18) 1301-1308 MAY 4 2000
Citations: 573
Title: ANTIRETROVIRAL THERAPY IN ADULTS - UPDATED RECOMMENDATIONS OF THE INTERNATIONAL AIDS SOCIETY-USA PANEL
Source: JAMA-J AM MED ASSN 283: (3) 381-390 JAN 19 2000
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Title: NAD(P)H OXIDASE - ROLE IN CARDIOVASCULAR BIOLOGY AND DISEASE
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Title: IRINOTECAN PLUS FLUOROURACIL AND LEUCOVORIN FOR METASTATIC COLORECTAL CANCER
source: N ENGL J MED 343: (13) 905-914 SEP 28 2000
Citations: 524
Title: IRINOTECAN COMBINED WITH FLUOROURACIL COMPARED WITH FLUOROURACIL ALONE AS FIRST-LINE TREATMENT FOR METASTATIC COLORECTAL CANCER: A MULTICENTRE RANDOMISED TRIAL
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Title: MOLECULAR CLASSIFICATION OF CUTANEOUS MALIGNANT MELANOMA BY GENE EXPRESSION PROFILING
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Title: NORMALIZING MITOCHONDRIAL SUPEROXIDE PRODUCTION BLOCKS THREE PATHWAYS OF HYPERGLYCAEMIC DAMAGE
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Title: EFFECTS OF RAMIPRIL ON CARDIOVASCULAR AND MICROVASCULAR OUTCOMES IN PEOPLE WITH DIABETES MELLITUS: RESULTS OF THE HOPE STUDY AND MICRO-HOPE SUBSTUDY
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Title: CD95'S DEADLY MISSION IN THE IMMUNE SYSTEM
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Title: EFFECTS OF ESTROGEN REPLACEMENT ON THE PROGRESSION OF CORONARY-ARTERY ATHEROSCLEROSIS
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2001
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Title: EXECUTIVE SUMMARY OF THE THIRD REPORT OF THE NATIONAL CHOLESTEROL EDUCATION PROGRAM (NCEP) EXPERT PANEL ON DETECTION, EVALUATION, AND TREATMENT OF HIGH BLOOD CHOLESTEROL IN ADULTS (ADULT TREATMENT PANEL III)
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Title: CANCER STATISTICS, 2001
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Title: EFFICACY AND SAFETY OF A SPECIFIC INHIBITOR OF THE BCR-ABL TYROSINE KINASE IN CHRONIC MYELOID LEUKEMIA
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Title: EFFICACY AND SAFETY OF RECOMBINANT HUMAN ACTIVATED PROTEIN C FOR SEVERE SEPSIS.
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Title: USE OF CHEMOTHERAPY PLUS A MONOCLONAL ANTIBODY AGAINST HER2 FOR METASTATIC BREAST CANCER THAT OVEREXPRESSES HER2
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Title: PREVENTION OF TYPE 2 DIABETES MELLITUS BY CHANGES IN LIFESTYLE AMONG SUBJECTS WITH IMPAIRED GLUCOSE TOLERANCE
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Title: EFFECTS OF LOSARTAN ON RENAL AND CARDIOVASCULAR OUTCOMES IN PATIENTS WITH TYPE 2 DIABETES AND NEPHROPATHY
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Title: ASSOCIATION OF NOD2 LEUCINE-RICH REPEAT VARIANTS WITH SUSCEPTIBILITY TO CROHN'S DISEASE
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Title: BONE MARROW CELLS REGENERATE INFARCTED MYOCARDIUM
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Title: A FRAMESHIFT MUTATION IN NOD2 ASSOCIATED WITH SUSCEPTIBILITY TO CROHN'S DISEASE
Source: NATURE 411: (6837) 603-606 MAY 31 2001
Citations: 663
Title: PEGINTERFERON ALFA-2B PLUS RIBAVIRIN COMPARED WITH INTERFERON ALFA-2B PLUS RIBAVIRIN FOR INITIAL TREATMENT OF CHRONIC HEPATITIS C: A RANDOMISED TRIAL
Source: LANCET 358: (9286) 958-965 SEP 22 2001
Citations: 500
Title: THE FAT-DERIVED HORMONE ADIPONECTIN REVERSES INSULIN RESISTANCE ASSOCIATED WITH BOTH LIPOATROPHY AND OBESITY
Source: NATURE MED 7: (8) 941-946 AUG 2001
Citations: 499
Title: THE EFFECT OF IRBESARTAN ON THE DEVELOPMENT OF DIABETIC NEPHROPATHY IN PATIENTS WITH TYPE 2 DIABETES
source: N ENGL J MED 345: (12) 870-878 SEP 20 2001
Citations: 486
Title: TUBERCULOSIS ASSOCIATED WITH INFLIXIMAB, A TUMOR NECROSIS FACTOR (ALPHA)-NEUTRALIZING AGENT
Source: N ENGL J MED 345: (15) 1098-1104 OCT 11 2001
Citations: 484
Title: INTENSIVE INSULIN THERAPY IN CRITICALLY ILL PATIENTS
Source: N ENGL J MED 345: (19) 1359-1367 NOV 8 2001
Citations: 471
Title: EFFECTS OF CLOPIDOGREL IN ADDITION TO ASPIRIN IN PATIENTS WITH ACUTE CORONARY SYNDROMES WITHOUT ST-SEGMENT ELEVATION.
Source: N ENGL J MED 345: (7) 494-502 AUG 16 2001
Citations: 470
Title: INVOLVEMENT OF CHEMOKINE RECEPTORS IN BREAST CANCER METASTASIS
Source: NATURE 410: (6824) 50-56 MAR 1 2001
Citations: 460
Title: CLINICAL RESISTANCE TO STI-571 CANCER THERAPY CAUSED BY BCR-ABL GENE MUTATION OR AMPLIFICATION
Source: SCIENCE 293: (5531) 876-880 AUG 3 2001
Citations: 457
Title: EFFECT OF CARVEDILOL ON SURVIVAL IN SEVERE CHRONIC HEART FAILURE.
Source: N ENGL J MED 344: (22) 1651-1658 MAY 31 2001
Citations: 452
Title: ONCOGENIC KINASE SIGNALLING
Source: NATURE 411: (6835) 355-365 MAY 17 2001
Citations: 441
Title: THE CONTINUING EPIDEMICS OF OBESITY AND DIABETES IN THE UNITED STATES
Source: JAMA-J AM MED ASSN 286: (10) 1195-1200 SEP 12 2001
Citations: 429
Title: EFFECTS OF ATORVASTATIN ON EARLY RECURRENT ISCHEMIC EVENTS IN ACUTE CORONARY SYNDROMES - THE MIRACL STUDY: A RANDOMIZED CONTROLLED TRIAL
Source: JAMA-J AM MED ASSN 285: (13) 1711-1718 APR 4 2001
Citations: 404
Title: REGENERATION OF ISCHEMIC CARDIAC MUSCLE AND VASCULAR ENDOTHELIUM BY ADULT STEM CELLS
Source: J CLIN INVEST 107: (11) 1395-1402 JUN 2001
Citations: 400
Title: ANTIGEN-SPECIFIC INHIBITION OF EFFECTOR T CELL FUNCTION IN HUMANS AFTER INJECTION OF IMMATURE DENDRITIC CELLS
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Citations: 399
Title: EFFECT OF THE TYROSINE KINASE INHIBITOR STI571 IN A PATIENT WITH A METASTATIC GASTROINTESTINAL STROMAL TUMOR
Source: N ENGL J MED 344: (14) 1052-1056 APR 5 2001
Citations: 397
Title: NEOVASCULARIZATION OF ISCHEMIC MYOCARDIUM BY HUMAN BONE-MARROW-DERIVED ANGIOBLASTS PREVENTS CARDIOMYOCYTE APOPTOSIS, REDUCES REMODELING AND IMPROVES CARDIAC FUNCTION
Source: NATURE MED 7: (4) 430-436 APR 2001
Citations: 396
Title: COMPARISON OF EARLY INVASIVE AND CONSERVATIVE STRATEGIES IN PATIENTS WITH UNSTABLE CORONARY SYNDROMES TREATED WITH THE GLYCOPROTEIN IIB/IIIA INHIBITOR TIROFIBAN
Source: N ENGL J MED 344: (25) 1879-1887 JUN 21 2001
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Citations: 1,692
Title: RISKS AND BENEFITS OF ESTROGEN PLUS PROGESTIN IN HEALTHY POSTMENOPAUSAL WOMEN - PRINCIPAL RESULTS FROM THE WOMEN'S HEALTH INITIATIVE RANDOMIZED CONTROLLED TRIAL
Source: JAMA-J AM MED ASSN 288: (3) 321-333 JUL 17 2002
Citations: 1,028
Title: CANCER STATISTICS, 2002
Source: CA-A CANCER J CLIN 52: (1) 23-47 JAN-FEB 2002
Citations: 1,001
Title: MRC/BHF HEART PROTECTION STUDY OF CHOLESTEROL LOWERING WITH SIMVASTATIN IN 20536 HIGH-RISK INDIVIDUALS: A RANDOMISED PLACEBO-CONTROLLED TRIAL
Source: LANCET 360: (9326) 7-22 JUL 6 2002
Citations: 896
Title: REDUCTION IN THE INCIDENCE OF TYPE 2 DIABETES WITH LIFESTYLE INTERVENTION OR METFORMIN
Source: N ENGL J MED 346: (6) 393-403 FEB 7 2002
Citations: 662
Title: GENE EXPRESSION PROFILING PREDICTS CLINICAL OUTCOME OF BREAST CANCER
Source: NATURE 415: (6871) 530-536 JAN 31 2002
Citations: 660
Title: CARDIOVASCULAR MORBIDITY AND MORTALITY IN THE LOSARTAN INTERVENTION FOR ENDPOINT REDUCTION IN HYPERTENSION STUDY (LIFE): A RANDOMISED TRIAL AGAINST ATENOLOL
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Citations: 568
Title: PREVALENCE AND TRENDS IN OBESITY AMONG US ADULTS, 1999-2000
Source: JAMA-J AM MED ASSN 288: (14) 1723-1727 OCT 9 2002
Citations: 558
Title: PLURIPOTENCY OF MESENCHYMAL STEM CELLS DERIVED FROM ADULT MARROW
Source: NATURE 418: (6893) 41-49 JUL 4 2002
Citations: 527
Title: MAJOR OUTCOMES IN HIGH-RISK HYPERTENSIVE PATIENTS RANDOMIZED TO ANGIOTENSIN-CONVERTING ENZYME INHIBITOR OR CALCIUM CHANNEL BLOCKER VS DIURETIC - THE ANTIHYPERTENSIVE AND LIPID-LOWERING TREATMENT TO PREVENT HEART ATTACK TRIAL (ALLHAT)
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Citations: 494
Title: A RANDOMIZED COMPARISON OF A SIROLIMUS-ELUTING STENT WITH A STANDARD STENT FOR CORONARY REVASCULARIZATION
Source: N ENGL J MED 346: (23) 1773-1780 JUN 6 2002
Citations: 492
Title: PREVALENCE OF THE METABOLIC SYNDROME AMONG US ADULTS - FINDINGS FROM THE THIRD NATIONAL HEALTH AND NUTRITION EXAMINATION SURVEY
Source: JAMA-J AM MED ASSN 287: (3) 356-359 JAN 16 2002
Citations: 471
Title: INFLAMMATION AND ATHEROSCLEROSIS
Source: CIRCULATION 105: (9) 1135-1143 MAR 5 2002
Citations: 463
Title: BONE MARROW CELLS ADOPT THE PHENOTYPE OF OTHER CELLS BY SPONTANEOUS CELL FUSION
Source: NATURE 416: (6880) 542-545 APR 4 2002
Citations: 452
Title: COLLABORATIVE META-ANALYSIS OF RANDOMISED TRIALS OF ANTIPLATELET THERAPY FOR PREVENTION OF DEATH, MYOCARDIAL INFARCTION, AND STROKE IN HIGH RISK PATIENTS
Source: BRIT MED J 324: (7329) 71-86 JAN 12 2002
Citations: 446
Title: USE OF PROTEOMIC PATTERNS IN SERUM TO IDENTIFY OVARIAN CANCER
Source: LANCET 359: (9306) 572-577 FEB 16 2002
Citations: 424
Title: HEMATOLOGIC AND CYTOGENETIC RESPONSES TO IMATINIB MESYLATE IN CHRONIC MYELOGENOUS LEUKEMIA
Source: N ENGL J MED 346: (9) 645-652 FEB 28 2002
Citations: 410
Title: PROPHYLACTIC IMPLANTATION OF A DEFIBRILLATOR IN PATIENTS WITH MYOCARDIAL INFARCTION AND REDUCED EJECTION FRACTION
Source: N ENGL J MED 346: (12) 877-883 MAR 21 2002
Citations: 407
Title: CHANGING POTENCY BY SPONTANEOUS FUSION
Source: NATURE 416: (6880) 545-548 APR 4 2002
Citations: 404
Title: PEGINTERFERON ALFA-2A PLUS RIBAVIRIN FOR CHRONIC HEPATITIS C VIRUS INFECTION
Source: N ENGL J MED 347: (13) 975-982 SEP 26 2002
Citations: 353
Title: COMPARISON OF C-REACTIVE PROTEIN AND LOW-DENSITY LIPOPROTEIN CHOLESTEROL LEVELS IN THE PREDICTION OF FIRST CARDIOVASCULAR EVENTS
Source: N ENGL J MED 347: (20) 1557-1565 NOV 14 2002
Citations: 351
Title: CARDIOVASCULAR DISEASE OUTCOMES DURING 6.8 YEARS OF HORMONE THERAPY - HEART AND ESTROGEN/PROGESTIN REPLACEMENT STUDY FOLLOW-UP (HERS II)
Source: JAMA-J AM MED ASSN 288: (1) 49-57 JUL 3 2002
Citations: 351
Title: MUTATIONS OF THE BRAF GENE IN HUMAN CANCER
Source: NATURE 417: (6892) 949-954 JUN 27 2002
Citations: 326
Title: CHOP CHEMOTHERAPY PLUS RITUXIMAB COMPARED WITH CHOP ALONE IN ELDERLY PATIENTS WITH DIFFUSE LARGE B-CELL LYMPHOMA
Source: N ENGL J MED 346: (4) 235-242JAN 24 2002
2003
Citations: 836
Title: CANCER STATISTICS, 2003
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Title: THE SEVENTH REPORT OF THE JOINT NATIONAL COMMITTEE ON PREVENTION, DETECTION, EVALUATION, AND TREATMENT OF HIGH BLOOD PRESSURE - THE JNC 7 REPORT
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Title: A NOVEL CORONAVIRUS ASSOCIATED WITH SEVERE ACUTE RESPIRATORY SYNDROME
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Title: IDENTIFICATION OF A NOVEL CORONAVIRUS IN PATIENTS WITH SEVERE ACUTE RESPIRATORY SYNDROME
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Citations: 390
Title: CORONAVIRUS AS A POSSIBLE CAUSE OF SEVERE ACUTE RESPIRATORY SYNDROME
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Title: A MAJOR OUTBREAK OF SEVERE ACUTE RESPIRATORY SYNDROME IN HONG KONG
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Title: CHARACTERIZATION OF A NOVEL CORONAVIRUS ASSOCIATED WITH SEVERE ACUTE RESPIRATORY SYNDROME
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