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Nicorandil may be associated with gastrointestinal ulceration

BMJ 2006; 332 doi: (Published 13 April 2006) Cite this as: BMJ 2006;332:889
  1. Mohaned Egred, specialist registrar in cardiology (,
  2. Mohammed Andron, cardiac clinical fellow1,
  3. W Lindsay Morrison, consultant cardiologist1
  1. 1 Cardiothoracic Centre, Liverpool L14 3PE
  1. Correspondence to: M Egred

    Nicorandil (Ikorel; Rhône-Poulenc Rorer, Guildford) is associated with mouth and anal ulcers,14 but we are not aware of any previous reports of association with gastrointestinal ulceration. A 69 year old woman had had percutaneous coronary intervention and a stent inserted into her left anterior descending artery two years before presentation. She had recurrent angina, and her general practitioner increased her dose of nicorandil to 30 mg twice a …

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