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Weight of evidence favours ketamine for children having fracture reduction

BMJ 2006; 332 doi: (Published 06 April 2006) Cite this as: BMJ 2006;332:0-e

Research question What is the best way to provide sedation and pain relief to children having a fracture reduced in the emergency department?

Answer It's hard to say for certain, but for systemic sedation and pain relief, ketamine plus midazolam seems safer and more effective than other combinations.

Why did the authors do the study? No consensus exists on the best way to provide children with sedation and pain relief during fracture reductions in the emergency department. These authors wanted to weigh up all the randomised evidence comparing different methods of sedation and pain relief to find out which was the safest and most effective.

What did …

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