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Nutritional supplements in cystic fibrosis

BMJ 2006; 332 doi: (Published 16 March 2006) Cite this as: BMJ 2006;332:618
  1. Matthias Kappler, paediatrician, division of gastroenterology and cystic fibrosis (,
  2. Matthias Griese, head of paediatric pulmonology
  1. Dr v Haunersches Kinderspital, Ludwig Maximilians University, 80337 Munich, Germany

    A new study suggests they're ineffective, but concordance may have been poor

    People with cystic fibrosis and their caregivers know that the better the patient's nutritional status, the better their survival, lung function, wellbeing, and mental capabilities.13 Poor nutrition is also associated with delayed puberty, a higher risk of pneumothorax, and a worse outcome after lung transplantation.4 5

    The increased demand for energy in cystic fibrosis is well recognised.6 Despite this, almost 20% of children with cystic fibrosis fall below the fifth centile for weight set by the Centers for Disease Control and Prevention,7 and their height and weight z scores often decline with age. Combating nutritional failure to ensure normal growth and weight gain …

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