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Does melatonin improve sleep?: Efficacy of melatonin

BMJ 2006; 332 doi: (Published 02 March 2006) Cite this as: BMJ 2006;332:550
  1. Josephine Arendtw, professor of endocrinology, emeritus (
  1. Centre for Chronobiology, School of Biomedical and Molecular Sciences, University of Surrey, Guildford, Surrey GU2 7XH

    EDITOR—Buscemi et al in their meta-analysis report that melatonin is ineffective in treating secondary sleep disorders or sleep disorders accompanying sleep restriction such as jet lag or shift work.1 The published reports in this domain certainly show some inconsistency, and now there is inconsistency in the meta-analyses.2 Numerous published studies, mostly with a positive result, have …

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