Intended for healthcare professionals


Pain is an issue in renal impairment

BMJ 2006; 332 doi: (Published 23 February 2006) Cite this as: BMJ 2006;332:488
  1. Colette Reid, research fellow in palliative medicine (,
  2. Jane Gibbins, specialist registrar, locum appointment training in palliative medicine,
  3. Geoffrey Hanks, professor of palliative medicine
  1. Department of Palliative Medicine, Bristol Oncology Centre, Bristol BS2 8ED

    EDITOR—Conway et al start their lesson of the week (that unrecognised accumulation of opiates in patients with renal failure may be life threatening) by saying that opiates and their metabolites accumulate in renal failure.1 Not all opioids behave in the same way: some, such as fentanyl, have no active metabolites and others, …

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