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We have used melatonin as part of multimodal therapy for inducing
sleep in ITU patients.It has worked in three out of three patients we
used,giving us a hundred percent success rate.Though this is a very small
number to say anything substantial,but certainly the result is
encouraging.We used melatonin only after traditional sedatives proved
ineffective in those three patients.The use of melatonin was along with
other sedatives and not on its own.