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Proton pump inhibitors match surgery in gastroesophageal reflux

BMJ 2006; 332 doi: (Published 05 January 2006) Cite this as: BMJ 2006;332:10
  1. Susan Mayor
  1. London

    Proton pump inhibitors are as effective as surgery in the management of gastroesophageal reflux disease, a report from the US Agency for Healthcare Research and Quality has found. The agency reviews the effectiveness of medical treatments used by Medicare, Medicaid, and the State Children's Health Insurance Program.

    The report reviewed treatments for chronic uncomplicated gastroesophageal reflux disease, which was defined as heartburn or acid regurgitation at least once a week. The report analysed randomised and non-randomised comparative studies, recent meta-analyses and cohort studies of over the counter drugs, proton pump inhibitors, fundoplication surgery (wrapping the top part of the stomach around the bottom of the oesophagus), …

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