Risk of gastrointestinal effects with COX-2 inhibitors and NSAIDs: How strong is the evidence?

BMJ 2005; 331 doi: https://doi.org/10.1136/bmj.331.7530.1474 (Published 15 December 2005) Cite this as: BMJ 2005;331:1474
  1. Bernard G Bannwarth, professor of therapeutics (bernard.bannwarth@u-bordeaux2.fr)
  1. University Hospital, 33076 Bordeaux, France

    EDITOR—The major conclusion drawn from the nested case-control study by Hippisley-Cox et al was that no consistent evidence was found of enhanced safety against gastrointestinal events with any of the new cyclo-oxygenase-2 (COX-2) inhibitors compared with non-selective non-steroidal anti-inflammatory …

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