Angioplasty prolongs survival in high risk patients with confirmed heart attackBMJ 2005; 331 doi: https://doi.org/10.1136/bmj.331.7530.0-e (Published 15 December 2005) Cite this as: BMJ 2005;331:0-e
Research question Can angioplasty reduce overall mortality compared with fibrinolysis in patients with heart attack?
Answer Yes. Primary angioplasty reduces overall mortality among patients identified as high risk by the TIMI (thrombolysis in myocardial infarction) score
Why did the authors do the study? Patients with confirmed heart attack who have a percutaneous coronary intervention are less likely to die or have another heart attack or stroke than patients treated with fibrinolytic drugs. But primary angioplasty is not widely available, and it's still unclear whether this invasive treatment reduces all cause mortality. These authors suspected that angioplasty was most likely to be life saving for patients at highest risk of death, and they did this …