Intended for healthcare professionals

News Roundup [abridged Versions Appear In The Paper Journal]

More drug trials end early hiding potential problems

BMJ 2005; 331 doi: (Published 10 November 2005) Cite this as: BMJ 2005;331:1103

This article has a correction. Please see:

  1. Michael Day
  1. London

    A growing number of trials sponsored by the drug industry are halted early on the grounds that apparent treatment benefits have emerged rapidly. The warning comes from Canadian researchers whose review of 143 randomised controlled trials has found a “frequent failure to report relevant information” and “implausibly large treatment effects” (JAMA 2005;294:2228-30).

    The proportion of randomised trials halted early has doubled in the past 10 years, from 0.5% in 1990-4 to 1.2% in 2000-4. And the scientific validity of the data they provide is not proved, say the researchers from McMaster University, Ontario, Canada.

    Dr Victor Montori, the lead …

    View Full Text

    Log in

    Log in through your institution


    * For online subscription