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Nearly half of patients with migraine with aura are found to have a heart defect, study finds

BMJ 2005; 331 doi: (Published 06 October 2005) Cite this as: BMJ 2005;331:800
  1. Roger Dobson
  1. Abergavenny

    A study has found that nearly half of a group of patients with long term migraine with aura had a heart defect. The defect was a right to left shunt caused by a patent foramen ovale.

    The study, by cardiologists and neurologists at University Hospital, Bern, Switzerland, appeared online ahead of print publication on 7 September in Neurology ( It used transoesophageal contrast echocardiography to examine the participants.

    The study looked at a group of 93 patients who had had migraine with aura for an average of 18.5 years and 93 healthy control patients …

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