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This Week In The Bmj

What works for malaria

BMJ 2005; 331 doi: (Published 29 September 2005) Cite this as: BMJ 2005;331:0-a

Guidelines for treating children with uncomplicated malaria changed in Zambia in 2002 in line with the best available evidence, but the change has not yet translated into adequate use at the point of care. A cross sectional study by Zurovac and colleagues (p 734) shows how artemether-lumefantrine, which should be the first choice of treatment for children weighing 10 kg or more, is not being prescribed even when available.

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In a cluster randomised trial, Chandramohan and colleagues (p 727) showed that sulfadoxine-pyrimethamine can prevent malaria and anaemia in infants up to 15 months old. These children may also have a higher risk of high parasite density malaria after treatment is stopped, however.