Intended for healthcare professionals


Obesity in middle age and future risk of dementia: Dietary fat and sugar may hold the clue

BMJ 2005; 331 doi: (Published 18 August 2005) Cite this as: BMJ 2005;331:454
  1. Naji Tabet, senior lecturer in old age psychiatry (
  1. Postgraduate Medical School, Faculty of Health, University of Brighton, Brighton BN1 9PH

    EDITOR—Whitmer et al report further evidence supporting the association between obesity and dementia.1 Although the mechanism is still far from being understood, the authors alluded to the involvement of adiposity with inflammation and its markers.

    One possible mechanism linking obesity with dementia is oxidative stress resulting from an increased intake of …

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