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Red eye

BMJ 2005; 331 doi: (Published 18 August 2005) Cite this as: BMJ 2005;331:438

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Leptospirosis eye disease - Doret Feigin Vitreopathy as diagnostic sign in red eye due to Leptospirosis

Red eye can be the initial manifestation of any disease. It is seen with a yellowish tinge in Leptospirosis and can be due to iritis or uveitis. We diagnosed an undiagnosed case of Leptospirosis from characteristic pathognomic Doret-Feigin Leptospira Vitreopathy, which was first described by Doret in 1951 and then Feigin in 1975 as a characteristic Leptospirosis vitreous involvement. Doret had classified uveitis due to leptospirosis into two forms: a mild anterior uveitis and panuveitis. Vitreous inflammatory cells aggregate to form vitreous exudates floating in vitreous, arranged in a linear pattern resembling a string of pearls and peculiar membranes.(1,3) These vitreous veil-like membranous opacities are either attached to the disc or they freely float in the vitreous. Feigin and Doret described membranous vitreous opacities to be the hallmark of the disease.(1,2)


1) Doret M, Rohm A. Augenkomplikationen bei benignen Leptospirosen. Klin Monatsbl Augenh 1951;118:51.
2) Feigin RD, Anderson DC, Human Leptospirosis. CRC Crit Rev Clin Lab Sci 1975;5:413-67.
3) Woods AC. Endogenous Uveitis . Baltimore: Williams & Wilkins; 1960. p. 76-8.
4) Sturman RM, Laval J, Weil VJ. Leptospiral Uveitis. Arch Ophthalmol 1959;61:633-9

Competing interests: No competing interests

21 August 2018
Sunil R Moreker
Eye surgeon
Harshvardhan Ghorpade
Fortis Hiranandani Vashi, Apollo Belapur, Nanavati Superspeciality, Seven hills , SL Raheja , Eyeris, Bhaktivedant , Conwest Jain Clini
Andheri , Mumbai , India