What's new this month in BMJ Journals

BMJ 2005; 331 doi: https://doi.org/10.1136/bmj.331.7513.372 (Published 11 August 2005) Cite this as: BMJ 2005;331:372
  1. Harvey Marcovitch, BMJ syndication editor (h.marcovitch@btinternet.com)

    Adding mesalazine enemas improves outcome in extensive ulcerative colitis

    A randomised placebo controlled trial has shown that adding a nightly mesalazine enema improves remission rates in patients with extensive ulcerative colitis who are already being treated with the oral preparation. After eight weeks, nearly 90% of those receiving combined treatment had improved (44% in remission) compared with under 70% of those having placebo enemas (34% in remission). Treatment was safe and well accepted, so should be considered as first line for those with colitis extending beyond the splenic flexure.

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    Beware of treating umbilical granulomas with silver nitrate

    Periumbilical ulceration in a 30 day old baby treated by her general practitioner with silver nitrate for an umbilical granuloma. The authors say that salt crystals are an effective …

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