Intended for healthcare professionals


Do selective serotonin reuptake inhibitors cause suicide?: Data seem to be incorrect

BMJ 2005; 330 doi: (Published 12 May 2005) Cite this as: BMJ 2005;330:1149
  1. Alex J Mitchell, consultant in liaison psychiatry (
  1. Leicester General Hospital, Leicester LE5 4PW

    EDITOR—Fergusson et al report that the risk of suicide attempts is significantly greater for patients enrolled in short term randomised controlled trials of selective serotonin reuptake inhibitors (SSRIs) than with placebo (odds ratio 2.28, P < 0.02) and other interventions (not including tricyclics) (odds ratio 1.94).1 They are also one of the few groups to report that completed suicides (fatal …

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