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Probiotic is useful for ulcerative colitis

BMJ 2005; 330 doi: (Published 05 May 2005) Cite this as: BMJ 2005;330:0-f

Question In patients with ulcerative colitis currently in remission, is the probiotic Escherichia coli Nissle 1917 as effective as standard treatment to prevent relapse?

Synopsis Probiotics are live, but non-pathogenic, micro-organisms that are used to alter the microbial balance in the intestinal tract. Although most probiotics are Gram positive species (Lactobacillus spp), E coli Nissle 1917 (EcN) is a Gram negative probiotic of a different strain than toxic E coli;it may work by causing an immune response or preventing invasion of other bacteria. The investigators …

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