Phenobarbital for epilepsy: much is still to be learnt

BMJ 2005; 330 doi: https://doi.org/10.1136/bmj.330.7495.846 (Published 07 April 2005) Cite this as: BMJ 2005;330:846
  1. Edward H Reynolds, honorary senior lecturer (reynolds@buckles.u-net.com)
  1. Institute of Epileptology, King's College, London SE5 6PJ

    EDITOR—Kale and Perucca contrast the widespread use of phenobarbital for epilepsy in the developing world with its disfavour in the developed world.1

    In the developing world up to two thirds or more of people with epilepsy receive no treatment at all.2 With limited resources and infrastructure health authorities' promotion of a cheap but effective drug, phenobarbital, is understandable and desirable. In developed countries the problem is often overtreatment. In the …

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