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Many wrong conclusions about the effects of treatments are due to
misinterpretation and a lack of understanding rather than to deliberate
fraud. This is surely where availability of the protocol will help in
reviewing reported trial results. As with any scientific experiment, the
most reliable way of ensuring the results are valid is for it to be
reproducible by others, and perhaps this is the only way of being certain
that the results of a particular trial are not deliberately manipulated.