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Gastric acid suppression is associated with increased risk of pneumonia

BMJ 2005; 330 doi: (Published 20 January 2005) Cite this as: BMJ 2005;330:0-f

Question Does use of acid suppressing drugs increase the risk of community acquired pneumonia

Synopsis Acid suppressing drugs, including H receptor antagonists (H2RAs) and proton pump inhibitors (PPIs), may increase the risk of bacterial colonisation of the gastrointestinal tract by increasing gastric pH. There is some evidence that acid suppression increases the risk of nosocomial infections, but few studies have been done in the outpatient setting. For this case-control trial, the authors gathered …

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