Traditional herbal medicines for malariaBMJ 2004; 329 doi: https://doi.org/10.1136/bmj.329.7475.1156 (Published 11 November 2004) Cite this as: BMJ 2004;329:1156
We identified quantitative studies on how often traditional plant based treatments for malaria were used, and results from all these studies were combined (as a meta-analysis) to give an overall average frequency of use. We added up the number of patients reporting the use of herbal medicines, and then we divided by the total number of patients surveyed in all the studies. We reviewed qualitative sociological and anthropological studies and extracted and summarised key themes.
We searched ethnobotanical studies from malaria endemic countries for plant species reported for the treatment of "malaria" or "fever". These we entered into a database and assigned an "IVmal" (importance value for the treatment of malaria) according to how widely its use was reported. Conservation information for each species came from the 2002 IUCN Red Data book online (www.redlist.org).
Clinical studies were categorised according to the study design (case reports, cohort studies, controlled trials) and to species of malaria. Each study was scrutinised for measures of efficacy (most commonly parasite clearance and clearance of fever or symptoms) and safety (reports of side effects or changes in haematological, biochemical, or electrocardiographical variables).
- How Botswana discovered the omicron variantBMJ September 26, 2023, 382 p1653; DOI: https://doi.org/10.1136/bmj.p1653
- Sudan’s worsening health conditions see children die of measles and malnutritionBMJ September 20, 2023, 382 p2158; DOI: https://doi.org/10.1136/bmj.p2158
- Covid-19: New “Pirola” variant BA.2.86 continues to spread in UK and USBMJ September 13, 2023, 382 p2097; DOI: https://doi.org/10.1136/bmj.p2097
- Helen Salisbury: Covid booster chaosBMJ September 05, 2023, 382 p2027; DOI: https://doi.org/10.1136/bmj.p2027
- Virtual wards: NICE sets out guidance on managing acute respiratory infections at homeBMJ September 04, 2023, 382 p2030; DOI: https://doi.org/10.1136/bmj.p2030
- Aqueous extract of Phyllanthus niruri protects against severe malaria by blocking erythrocyte invasion and modulating the host immune response
- Acute adrenal failure: a potentially fatal consequence of an adulterated herbal remedy
- From crystal to compound: structure-based antimalarial drug discovery
- Antiplasmodial Activity of Aryltetralone Lignans from Holostylis reniformis