Re: What causes chronic fatigue syndrome?
Some time has elapsed since this editorial was written, and it may be relevant now to point out that 30,000 cases of post-traumatic hypopituitarism are missed each year, and many of them are misdiagnosed with chronic fatigue syndrome http://dailym.ai/1gWRisu The incidence of PTHP is between 30 and 50 per 100,000 so the prevalence in the UK may, after decades of neglect, be around a million. If these people were removed from the CFS equation we might well see the prevalence of ME/CFS/fibromyalgia reduced by a third. Several hypopituitarism patients who have experienced an ME misdiagnosis have written to the BMJ and their stories may be found on these links:
Schneider HJ et al, Hypothalamopituitary Dysfunction Following Traumatic Brain Injury and Aneurysmal Subarachnoid Haemorrhage: A Systematic Review, 2007, JAMA
Fernandez-Rodriguez E et al, Hypopituitarism following traumatic brain injury: determining factors for diagnosis, Front Endocrinol 25 August 2011 doi: 10.3389/fendo.2011.00025
Competing interests: No competing interests