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Evidence is wrong if there are counterexamples to it. This is a time honored concept by Sir Karl Popper, who was knighted for his philosophy on science. Counterexamples play an active role in correcting, limiting, or modifying all sciences except in medicine where they are ignored or dismissed as mere anecdotes.
Re: Grading quality of evidence and strength of recommendations
Evidence is wrong if there are counterexamples to it. This is a time honored concept by Sir Karl Popper, who was knighted for his philosophy on science. Counterexamples play an active role in correcting, limiting, or modifying all sciences except in medicine where they are ignored or dismissed as mere anecdotes.
Competing interests: No competing interests