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Risk of heart failure may be lower with celecoxib than with other NSAID

BMJ 2004; 328 doi: (Published 03 June 2004) Cite this as: BMJ 2004;328:1338
  1. Barbara Kermode-Scott
  1. Toronto

    The anti-inflammatory cyclo-oxygenase-2 (COX 2) inhibitor celecoxib may be associated with a lower risk of congestive heart failure in the elderly than other non-steroidal anti-inflammatory drugs (NSAIDs), a large new Canadian study has found.

    This study, published online on 29 May in the Lancet (, was funded by the Canadian Institutes of Health Research.

    “Our findings suggest significant differences between non-selective NSAIDs and individual COX 2 inhibitors with respect to risk of admission for congestive heart failure,” said the study's lead author, Professor Muhammad Mamdani, assistant professor in clinical epidemiology and healthcare research, …

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