Fillers POEM

Strontium reduces risk of symptomatic vertebral fracture

BMJ 2004; 328 doi: (Published 13 May 2004) Cite this as: BMJ 2004;328:0-e

Question Does strontium ranelate improve clinical outcomes in patients with postmenopausal osteoporosis and at least one vertebral fracture?

Synopsis Strontium ranelate is thought to both increase the formation of new bone and decrease bone resorption. In this double blind, randomised controlled trial postmenopausal women with osteoporosis and at least one vertebral compression fracture were randomly assigned (allocation concealment uncertain) to 2 g strontium powder a day or placebo. The powder could be taken once or twice daily, and follow up consisted of annual radiographs and patients' …

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