Folic acid as ultimate in disease prevention:Beware of vitamin B12 deficiency

BMJ 2004; 328 doi: https://doi.org/10.1136/bmj.328.7442.769 (Published 25 March 2004) Cite this as: BMJ 2004;328:769
  1. Stephen Malnick, director (stevash@tredline.co.il),
  2. Sorel Goland, senior cardiologist (stevash@tredline.co.il)
  1. Kaplan Medical Centre, Rehovot 76100, Israel
  2. department of internal medicine C, heart institute, Kaplan Medical Centre, Rehovot 76100, Israel

    EDITOR—In response to the review by Lucock on folic acid supplementation,1 we have a word of caution about possible concomitant vitamin B12 deficiency, which may also cause raised concentrations of homocysteine.

    Vitamin B12 deficiency can be subtle, manifesting only as an increase in concentrations of homocysteine …

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