News Roundup

Oestrogen only arm of women's health initiative trial is stopped

BMJ 2004; 328 doi: (Published 11 March 2004) Cite this as: BMJ 2004;328:602
  1. Janice Hopkins Tanne
  1. New York

    The oestrogen only study of the women's health initiative study sponsored by the US National Institutes of Health has been stopped early because of a slightly increased risk of stroke among women in the trial. The study included only women who did not have a uterus.

    Dr Barbara Alving, director of the women's health initiative and acting director of the National Heart, Lung, and Blood Institute, said the study was stopped because treatment with oestrogen neither increased nor decreased the risk of heart disease, a question the study sought to answer.

    The study, which involved nearly 11 000 women, showed that oestrogen only treatment did not increase the risk of breast cancer during the seven years of the study and reduced the risk …

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