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People with sickle cell disease should be screened for pulmonary hypertension

BMJ 2004; 328 doi: (Published 04 March 2004) Cite this as: BMJ 2004;328:543
  1. Scott Gottlieb
  1. New York

    Pulmonary hypertension has been identified as a major risk factor for death in adults with sickle cell disease, and all people with the disease should be screened for this complication, a new study says.

    Almost a third of adult patients with sickle cell disease who were screened with Doppler echocardiography were found to have moderate to severe pulmonary hypertension that had not previously been detected (New England Journal of Medicine 2004;350:886-95).

    The researchers assessed pulmonary artery systolic pressure in 195 consecutive patients (82 men and 113 women with a mean (SD) age of 36 (12) years). Patients …

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