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  1. Where is the evidence...
  2. Where is the evidence that animal research benefits humans?
Education And Debate

Where is the evidence that animal research benefits humans?

BMJ 2004; 328 doi: https://doi.org/10.1136/bmj.328.7438.514 (Published 26 February 2004) Cite this as: BMJ 2004;328:514

Data supplement

  • Details of Medline search for systematic reviews of animal studies 1966 - November 2003

    1. Disease Models, Animal/

    2. (animal$ adj3 model$).tw.

    3. (animal$ adj3 (study or studies)).tw.

    4. (animal adj3 trial$).tw.

    5. (animal$ adj3 experiment$). tw.

    6. (systematic$ adj3 review$).tw. 7. meta-analysis/

    8. meta-analysis.tw.

    9. metanalysis.tw.

    10. metaanalysis.tw.

    11. Review Literature/

    12. Meta-analysis.pt.

    13. (systematic$ adj3 overview$).tw.

    14. pool$ data.tw.

    15. or/1-5

    16. or/6-14

    17. 15 and 16

    1. Freedman LS, Clifford CK. Meta-analysis of animal experiments: elucidating relationships between dietary fat and mammary tumor development in rodents. Adv Exp Med Biol 1994;364:93-100.
    2. Kelley G. Mechanical overload and skeletal muscle fiber hyperplasia: a meta-analysis. J Appl Physiol 1996;81:1584-8.
    3. Glatt SJ, Bolanos CA, Trksak GH, Jackson D. Effects of prenatal cocaine exposure on dopamine system development: a meta-analysis. Neurotoxicol Teratol 2000;22:617-29.
    4. Nava-Ocampo AA, Reyes-Perez H, Bello-Ramirez AM, Mansilla-Olivares AM, Ponce-Monter H. For ischemic brain damage, is preclinical evidence of neuroprotection by presynaptic blockade of glutamate release enough? Med Hypoth 2000;54(1):77-9.
    5. Boissier J, Mone H. Relationship between worm burden and male proportion in Schistosoma mansoni experimentally infected rodents and primates. A meta-analytical approach. Int J Parasitol 2001;31:1597-9.
    6. Aghajafari F, Murphy K, Matthews S, Ohlsson A, Amankwah K, Hannah M. Repeated doses of antenatal corticosteroids in animals: a systematic review. J Obstet Gynaecol 2002;186:843-9.
    7. Meune C, Spaulding C, Mahe I, Lebon P, Bergmann J-F. Risks versus benefits of NSAIDs including aspirin in myocarditis. A review of the evidence from animal studies. Drug Safety 2003;26:975-81.
    8. Corpet DE, Tache S. Most effective colon cancer chemopreventive agents in rats: a systematic review of aberrant crypt foci and tumor data, ranked by potency. Nutr Cancer 2002;43:1-21.
    9. Corpet DE, Pierre F. From animal models to prevention of colon cancer. Systematic review of chemoprevention in Min Mice and choice of the model system. Cancer Epidemiol Biomarkers Prev 2003;12:391-400.
    10. Dirx MJ, Zeegers MP, Dagnelie PC, van den Bogaard T, van den Brandt PA. Energy restriction and the risk of spontaneous mammary tumors in mice: a meta-analysis. Int J Cancer 2003;106:766-70.
    11. Vittek J. Effect of royal jelly on serum lipids in experimental animals and humans with atherosclerosis. Experientia 1995;51:927-35.
    12. Collins JJ, Ness R, Tyl RW, Krivanek N, Esmen NA, Hall TA. A review of adverse pregnancy outcomes and formaldehyde exposure in human and animal studies. Regulatory Toxicol Pharmacol 2001;34:17-34.
    13. Blackman K, Brown SGA, Wilkes GJ. Plasma alkalinization for tricyclic antidepressant toxicity: a systematic review. Emerg Med 2001;13:204-10.
    14. Fox CH, Eberl M. Phytic acid (IP6), novel broad spectrum anti-neoplastic agent: a systematic review. Complement Ther Med 2002;10:229-34.
    15. Klinge B, Gustafsson KB, Berglundh T. A systematic review of the effect of anti-infective therapy in the treatment of peri-implantitis. J Clin Periodontol 2002;29(suppl 3):213-25.
    16. Borrelli F, Ernst E. Cimicifuga racemosa: a systematic review of its clinical efficacy. Eur J Clin Pharmacol 2002;58:235-41.
    17. Ren Y, Maltha JC, Kuijpers-Jagtman AM. Optimum force magnitude for orthodontic tooth movement: a systematic literature review. Angle Orthodontist 2003;73(1):86-92.
    18. Bailey B. Glucagon in α –blocker and calcium channel blocker overdoses. A systematic review. J Toxicol–Clin Toxicol 2003;41:595-602.

     

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