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Clinical Review Interactive case report

Treating nausea and vomiting during pregnancy: case outcome

BMJ 2004; 328 doi: (Published 26 February 2004) Cite this as: BMJ 2004;328:503
  1. Nicola Harker, general practitioner1,
  2. Alan Montgomery, lecturer in primary care research2,
  3. Tom Fahey, professor of primary care medicine (
  1. 1Dean Lane Family Practice, Bedminster, Bristol
  2. 2Division of Primary Health Care, University of Bristol
  3. 3Tayside Centre for General Practice, University of Dundee, Dundee DD2 4AD
  1. Correspondence to: T Fahey

    Five weeks ago (31 January, p 276) we presented the case of Ms Reynolds, a 25 year old woman who presented to her general practitioner when eight weeks pregnant complaining of nausea and vomiting with light headedness.After an unsuccessful trial of prochlorperazine, she asked about alternatives to conventional drugs, and we suggested a trial of vitamin B-6 (pyridoxine) to relieve her symptoms (7 February, p 337). Because of the paucity of evidence for or against the use of vitamin B-6, we suggested an n of 1 trial as an objective way to assess whether it was effective. The table shows that vitamin B-6 did …

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