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Risk of suicide in bipolar disorder is least with lithium

BMJ 2004; 328 doi: (Published 12 February 2004) Cite this as: BMJ 2004;328:0-e

Question Which drug used to treat bipolar disorder is most effective for reducing the risk of suicide?

Synopsis The use of lithium in the treatment of bipolar disorder has decreased as the use of anticonvulsants has steadily increased. Consistent evidence shows that lithium is effective for reducing the risk of suicide, but little is known about other agents. In this retrospective cohort study, the authors wanted to compare the risk of a suicide attempt and death …

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