Another HRT trial is stopped early

BMJ 2004; 328 doi: (Published 05 February 2004) Cite this as: BMJ 2004;328:305
  1. Owen Dyer
  1. London

Another trial of hormone replacement therapy (HRT) has been stopped early by researchers after preliminary findings showed an “unacceptably high risk” of recurrent or new breast cancer associated with the treatment.

The Swedish HABITS (hormonal replacement therapy after breast cancer diagnosis—is it safe?) study was intended to follow 1300 women previously treated successfully for breast cancer. Only 434 women had been randomised when it was stopped on 17 December 2003, two years into its planned five year course. By that stage, 26 participants had developed breast cancer out of 174 …

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