Stress and exacerbations in multiple sclerosis

BMJ 2004; 328 doi: https://doi.org/10.1136/bmj.328.7434.287-a (Published 29 January 2004) Cite this as: BMJ 2004;328:287

Authors' reply

  1. R Q Hintzen, neurologist (rhintzen@xs4all.nl),
  2. D Buljevac, medical doctor,
  3. W C J Hop, biostatistician,
  4. A C J W Janssens, psychologist
  1. Department of Neurology, Erasmus MC, Postbox 2040, 3000 CA Rotterdam, Netherlands
  2. Department of Epidemiology and Biostatistics, Erasmus MC
  3. Department of Medical Psychology and Psychotherapy, Erasmus MC

    EDITOR—We agree with Galea et al that recall bias could be an alternative explanation for our finding that stressful events are associated with the risk of exacerbation in multiple sclerosis.

    To minimise the possibility of recall bias we chose a high (weekly) sampling frequency. Nevertheless, when patients experienced an event and still had …

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