Stress and exacerbations in multiple sclerosis

BMJ 2004; 328 doi: https://doi.org/10.1136/bmj.328.7434.287 (Published 29 January 2004) Cite this as: BMJ 2004;328:287

Whether stress triggers relapses remains a conundrum

  1. Ian Galea, research assistant (igalea@soton.ac.uk),
  2. Tracey A Newman, postdoctoral scientist,
  3. Yori Gidron, senior lecturer
  1. CNS Inflammation Group, University of Southampton, Southampton SO16 7PX
  2. School of Psychology, University of Southampton, Southampton SO17 1BJ

    EDITOR—The front page of the BMJ of 20 September 2003 carries the title: “Relapse in multiple sclerosis: stressful life events increase exacerbations.” Buljevac et al present evidence that psychological stress is associated with a doubling in risk of relapse.1 Two issues arise.

    Firstly, this study has limitations, some of which are clearly acknowledged by …

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