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Prescription of heroin to treatment resistant heroin addicts

BMJ 2004; 328 doi: (Published 22 January 2004) Cite this as: BMJ 2004;328:228

Dutch heroin trials show retention is better with methadone alone

  1. John Caplehorn (, senior lecturer
  1. Clinical Epidemiology, School of Public Health, A27 University of Sydney, Sydney, NSW 2006, Australia

    EDITOR—The conclusion by van den Brink et al that medical co-prescription of heroin to treatment resistant heroin addicts was more effective than methadone alone is not supported by all of their data.1 Rather, the better quality retention data significantly favour the methadone only group.

    The trialists' claim that heroin co-prescription is superior to routine methadone maintenance is based …

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